Copy number neutral loss of heterozygosity (CN-LOH) 17p and homozygous mutations of TP53 gene are associated with complex chromosomal aberrations (CCA) in newly diagnosed myelodysplastic syndromes (MDS)

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F16%3A00011402" target="_blank" >RIV/00023736:_____/16:00011402 - isvavai.cz</a>
Result on the web
<a href="http://dx.doii.org/10.1016/j.leukres.2016.01.009" target="_blank" >http://dx.doii.org/10.1016/j.leukres.2016.01.009</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.leukres.2016.01.009" target="_blank" >10.1016/j.leukres.2016.01.009</a>

Result language
angličtina
Original language name
Copy number neutral loss of heterozygosity (CN-LOH) 17p and homozygous mutations of TP53 gene are associated with complex chromosomal aberrations (CCA) in newly diagnosed myelodysplastic syndromes (MDS)
Original language description
The aim of our study was to evaluate the frequency of CN-LOH 17p in bone marrow cells of newly diagnosed MDS patients with complex chromosomal aberrations and to assess its correlation with mutations of TP53 gene (17p13.1).
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Project
<a href="/en/project/NT14377" target="_blank" >NT14377: Prediction of the response to demethylation treatment in patients with myelodysplastic syndromes using integrative genomics</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Result description