AFLP-AFLP in silico-NGS approach reveals polymorphisms in repetitive elements in the malignant genome

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F18%3A00012441" target="_blank" >RIV/00023736:_____/18:00012441 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1371/journal.pone.0206620" target="_blank" >https://doi.org/10.1371/journal.pone.0206620</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1371/journal.pone.0206620" target="_blank" >10.1371/journal.pone.0206620</a>

Result language
angličtina
Original language name
AFLP-AFLP in silico-NGS approach reveals polymorphisms in repetitive elements in the malignant genome
Original language description
In this work, we established an approach combining amplified fragment length polymorphism (AFLP), AFLP in silico and next generation sequencing (NGS) methods to map the malignant genome of patients with chronic myeloid leukemia. We compared the unique DNA fingerprints of patients generated by the AFLP technique approach with those of healthy donors to identify AFLP markers associated with the disease and/or the response to treatment with imatinib, a tyrosine kinase inhibitor.
Czech name
—
Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30205 - Hematology

Project
<a href="/en/project/NT11555" target="_blank" >NT11555: DNA fingerprinting in chronic myeloid leukemia</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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