Hematopoietic stem cell transplantation from haploidentical donors in aplasia after cladribine/cytarabine chemotherapy for refractory acute myeloid leukemia or myelodysplastic syndrome
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F19%3A00012757" target="_blank" >RIV/00023736:_____/19:00012757 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1016/j.clml.2019.02.005" target="_blank" >https://doi.org/10.1016/j.clml.2019.02.005</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.clml.2019.02.005" target="_blank" >10.1016/j.clml.2019.02.005</a>
Alternative languages
Result language
angličtina
Original language name
Hematopoietic stem cell transplantation from haploidentical donors in aplasia after cladribine/cytarabine chemotherapy for refractory acute myeloid leukemia or myelodysplastic syndrome
Original language description
Survival rate of patients with chemorefractory acute myeloid leukemia (AML) or myelodysplastic syndrome with excess blasts (MDS-EB) is poor. Allogeneic hematopoietic cell transplantation (HCT) is the only potentially curative therapy in these patients. We report a retrospective analysis of outcomes of therapy of 24 patients with AML or MDS-EB refractory to high-dose salvage chemotherapy or who had failed previous HCT, who received T-cell–replete HLA haploidentical HCT in aplasia after cladribine/cytarabine-based chemotherapy followed by reduced intensity or myeloablative conditioning. All patients had active disease before commencement of the treatment.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30205 - Hematology
Result continuities
Project
<a href="/en/project/NV16-34405A" target="_blank" >NV16-34405A: Adoptive immunotherapy of hematological malignancies in elderly patients: preclinical and clinical study</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Clinical lymphoma, myeloma & leukemia
ISSN
2152-2650
e-ISSN
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Volume of the periodical
19
Issue of the periodical within the volume
6
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
365-371
UT code for WoS article
000473284900016
EID of the result in the Scopus database
2-s2.0-85063048048