Immunophenotyping of paroxysmal nocturnal hemoglobinuria (PNH)

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F19%3A00012788" target="_blank" >RIV/00023736:_____/19:00012788 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1007/978-1-4939-9650-6_18" target="_blank" >https://doi.org/10.1007/978-1-4939-9650-6_18</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-1-4939-9650-6_18" target="_blank" >10.1007/978-1-4939-9650-6_18</a>

Result language
angličtina
Original language name
Immunophenotyping of paroxysmal nocturnal hemoglobinuria (PNH)
Original language description
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare but often debilitating disease which may lead to death in up to 35% of patients within 5 years if unrecognized and untreated. Detection of PNH and assessment of PNH clone size in RBC and WBC lineages by flow cytometric analysis has increased in importance due to the availability of novel therapies. These therapies typically block the hemolysis of red blood cells and thus significantly lower the morbidities and mortality associated with this disease. This chapter describes validated, state-of-the-art, high-sensitivity flow cytometric methodologies based on latest published testing guidelines for PNH.
Czech name
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Czech description
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Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
30205 - Hematology

Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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