Circulating small noncoding RNAs have specific expression patterns in plasma and extracellular vesicles in myelodysplastic syndromes and are predictive of patient outcome
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F20%3A00012997" target="_blank" >RIV/00023736:_____/20:00012997 - isvavai.cz</a>
Alternative codes found
RIV/68407700:21230/20:00341620 RIV/00216208:11110/20:10414028 RIV/00216208:11310/20:10414028 RIV/00064165:_____/20:10414028
Result on the web
<a href="https://doi.org/10.3390/cells9040794" target="_blank" >https://doi.org/10.3390/cells9040794</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/cells9040794" target="_blank" >10.3390/cells9040794</a>
Alternative languages
Result language
angličtina
Original language name
Circulating small noncoding RNAs have specific expression patterns in plasma and extracellular vesicles in myelodysplastic syndromes and are predictive of patient outcome
Original language description
Myelodysplastic syndromes (MDS) are hematopoietic stem cell disorders with large heterogeneity at the clinical and molecular levels. As diagnostic procedures shift from bone marrow biopsies towards less invasive techniques, circulating small noncoding RNAs (sncRNAs) have become of particular interest as potential novel noninvasive biomarkers of the disease. We aimed to characterize the expression profiles of circulating sncRNAs of MDS patients and to search for specific RNAs applicable as potential biomarkers. We performed small RNA-seq in paired samples of total plasma and plasma-derived extracellular vesicles (EVs) obtained from 42 patients and 17 healthy controls and analyzed the data with respect to the stage of the disease, patient survival, response to azacitidine, mutational status, and RNA editing.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30205 - Hematology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Cells
ISSN
2073-4409
e-ISSN
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Volume of the periodical
9
Issue of the periodical within the volume
4
Country of publishing house
CH - SWITZERLAND
Number of pages
26
Pages from-to
"art. no. E794"
UT code for WoS article
000535559500005
EID of the result in the Scopus database
2-s2.0-85089080240