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Targeted volatolomics of human monocytes: comparison of 2D-GC/TOF-MS and 1D-GC/Orbitrap-MS methods

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F21%3A00013292" target="_blank" >RIV/00023736:_____/21:00013292 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216305:26620/21:PU142159 RIV/61388955:_____/21:00549181 RIV/00159816:_____/21:00075074 RIV/62156489:43210/21:43920397 RIV/62156489:43410/21:43920397

  • Result on the web

    <a href="https://doi.org/10.1016/j.jchromb.2021.122975" target="_blank" >https://doi.org/10.1016/j.jchromb.2021.122975</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.jchromb.2021.122975" target="_blank" >10.1016/j.jchromb.2021.122975</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Targeted volatolomics of human monocytes: comparison of 2D-GC/TOF-MS and 1D-GC/Orbitrap-MS methods

  • Original language description

    Blood is a complex biological matrix providing valuable information on nutritional, metabolic, and immune status. The detection of blood biomarkers requires sensitive analytical methods because analytes are at very low concentrations. Peripheral blood monocytes play a crucial role in inflammatory processes, and the metabolites released by monocytes during these processes might serve as important signalling molecules and biomarkers of particular physiological states. Headspace solid-phase microextraction (HS-SPME) combined with two different mass spectrometric platforms, two-dimensional (2D) gas chromatography coupled to time-of-flight mass spectrometry (2D-GC/TOF-MS) and one-dimensional gas chromatography coupled to Orbitrap mass spectrometry (GC/Orbitrap-MS), were applied for the investigation of volatile organic compounds (VOCs) produced by human peripheral blood monocytes.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30205 - Hematology

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of chromatography B: analytical technologies in the biomedical and life sciences

  • ISSN

    1570-0232

  • e-ISSN

  • Volume of the periodical

    1184

  • Issue of the periodical within the volume

    [November]

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    10

  • Pages from-to

    "art. no. 122975"

  • UT code for WoS article

    000710634000005

  • EID of the result in the Scopus database

    2-s2.0-85118774008