All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

NPM1 and DNMT3A mutations are associated with distinct blast immunophenotype in acute myeloid leukemia

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F22%3A00013399" target="_blank" >RIV/00023736:_____/22:00013399 - isvavai.cz</a>

  • Result on the web

    <a href="https://doi.org/10.1080/2162402X.2022.2073050" target="_blank" >https://doi.org/10.1080/2162402X.2022.2073050</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1080/2162402X.2022.2073050" target="_blank" >10.1080/2162402X.2022.2073050</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    NPM1 and DNMT3A mutations are associated with distinct blast immunophenotype in acute myeloid leukemia

  • Original language description

    The immune system is important for elimination of residual leukemic cells during acute myeloid leukemia (AML) therapy. Anti-leukemia immune response can be inhibited by various mechanisms leading to immune evasion and disease relapse. Selected markers of immune escape were analyzed on AML cells from leukapheresis at diagnosis (N = 53). Hierarchical clustering of AML immunophenotypes yielded distinct genetic clusters. In the absence of DNMT3A mutation, NPM1 mutation was associated with decreased HLA expression and low levels of other markers (CLIP, PD-L1, TIM-3).

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30205 - Hematology

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2022

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    OncoImmunology

  • ISSN

    2162-4011

  • e-ISSN

  • Volume of the periodical

    11

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    14

  • Pages from-to

    "art. no. e2073050"

  • UT code for WoS article

    000791587400001

  • EID of the result in the Scopus database

    2-s2.0-85129870307