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Hepcidin and ferritin levels as markers of immune cell activation during septic shock, severe COVID-19 and sterile inflammation

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F23%3A00013512" target="_blank" >RIV/00023736:_____/23:00013512 - isvavai.cz</a>

  • Alternative codes found

    RIV/00159816:_____/23:00079723 RIV/00216224:14110/23:00130268

  • Result on the web

    <a href="https://doi.org/10.3389/fimmu.2023.1110540" target="_blank" >https://doi.org/10.3389/fimmu.2023.1110540</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.3389/fimmu.2023.1110540" target="_blank" >10.3389/fimmu.2023.1110540</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Hepcidin and ferritin levels as markers of immune cell activation during septic shock, severe COVID-19 and sterile inflammation

  • Original language description

    Major clinically relevant inflammatory events such as septic shock and severe COVID-19 trigger dynamic changes in the host immune system, presenting promising candidates for new biomarkers to improve precision diagnostics and patient stratification. Hepcidin, a master regulator of iron metabolism, has been intensively studied in many pathologies associated with immune system activation, however these data have never been compared to other clinical settings. Thus, we aimed to reveal the dynamics of iron regulation in various clinical settings and to determine the suitability of hepcidin and/or ferritin levels as biomarkers of inflammatory disease severity.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30205 - Hematology

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Frontiers in immunology

  • ISSN

    1664-3224

  • e-ISSN

  • Volume of the periodical

    14

  • Issue of the periodical within the volume

    January

  • Country of publishing house

    CH - SWITZERLAND

  • Number of pages

    10

  • Pages from-to

  • UT code for WoS article

    000929110400001

  • EID of the result in the Scopus database

    2-s2.0-85147753161