Applicability of gene expression in saliva as an alternative to blood for biodosimetry and prediction of radiation-inducede health effects
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F24%3A00013665" target="_blank" >RIV/00023736:_____/24:00013665 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1667/RADE-23-00176.1" target="_blank" >https://doi.org/10.1667/RADE-23-00176.1</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1667/RADE-23-00176.1" target="_blank" >10.1667/RADE-23-00176.1</a>
Alternative languages
Result language
angličtina
Original language name
Applicability of gene expression in saliva as an alternative to blood for biodosimetry and prediction of radiation-inducede health effects
Original language description
As the great majority of gene expression (GE) biodosimetry studies have been performed using blood as the preferred source of tissue, searching for simple and less-invasive sampling methods is important when considering biodosimetry approaches. Knowing that whole saliva contains an ultrafiltrate of blood and white blood cells, it is expected that the findings in blood can also be found in saliva. This human in vivo study aims to examine radiation-induced GE changes in saliva for biodosimetry purposes and to predict radiation-induced disease, which is yet poorly characterized. Furthermore, we examined whether transcriptional biomarkers in blood can also be found equivalently in saliva.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30205 - Hematology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Radiation research
ISSN
0033-7587
e-ISSN
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Volume of the periodical
201
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
12
Pages from-to
523-534
UT code for WoS article
001226507700017
EID of the result in the Scopus database
2-s2.0-85192675519