Peripheral blood stem cell versus bone marrow graft for patients ≥60 years undergoing reduced intensity conditioning haploidentical transplantation for acute myeloid leukemia in complete remission: an analysis of the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F24%3A00013672" target="_blank" >RIV/00023736:_____/24:00013672 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1002/ajh.27343" target="_blank" >https://doi.org/10.1002/ajh.27343</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/ajh.27343" target="_blank" >10.1002/ajh.27343</a>
Alternative languages
Result language
angličtina
Original language name
Peripheral blood stem cell versus bone marrow graft for patients ≥60 years undergoing reduced intensity conditioning haploidentical transplantation for acute myeloid leukemia in complete remission: an analysis of the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation
Original language description
In the context of T-cell replete haploidentical stem cell transplantation (Haplo-SCT) using post-transplantation cyclophosphamide (PT-Cy), it is still unknown whether peripheral blood (PB) or bone marrow (BM) is the best graft source. While PB is associated with a higher incidence of graft-versus-host disease (GVHD), it may induce a stronger graft-versus-leukemia effect compared to BM, notably in acute myeloid leukemia (AML). We conclude that in the specific context of Haplo-SCT with PT-Cy, PB grafts represent a valid option to decrease the risk of relapse and improve outcome of older AML patients who usually do not benefit from conditioning intensification.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30205 - Hematology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
American journal of hematology
ISSN
0361-8609
e-ISSN
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Volume of the periodical
99
Issue of the periodical within the volume
7
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
1250-1256
UT code for WoS article
001229155000001
EID of the result in the Scopus database
2-s2.0-85193922427