Repetitive transcranial magnetic stimulation (rTMS) - influence on the brain metabolism

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F03%3A00000277" target="_blank" >RIV/00023752:_____/03:00000277 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Repetitive transcranial magnetic stimulation (rTMS) - influence on the brain metabolism
Original language description
We investigated the influence of the 3 week series of high and low frequency rTMS on the basal brain metabolism in the group of patients with depression and obsessive compulsive disorder (OCD). In accordance with the neuroimaging data indicating that depressive disorder is connected with decrease brain metabolism and OCD with increased frontal metabolism we applied the low (1 Hz) frequency in OCD and high frequency (20 Hz) in case of depressive disorder. rTMS was applied with 100% of motor threshold measured by standard method using the EMG control. The high frequency was defined as 20Hz, 2 s train and 18 s intertrain interval (the total number of stimuli 1800). The low frequency was defined as 1 Hz (total number of stimuli 900). The total number of rTMS sessions was 15. The psychopathology was measured by the psychometric scales (HAMA, HAMD, Y-BOCS, CGI). 18 fluoro-deoxy-glucose (18FDG) positron emission tomography (PET) was performed before and after the rTMS treatment. The statistic
Czech name
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Czech description
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Project
<a href="/en/project/LN00B122" target="_blank" >LN00B122: Neuropsychiatric Research Center</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2003
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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