Social interaction deficits in schizophrenia-spectrum disorders and pharmacologic intervention

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F09%3A00001023" target="_blank" >RIV/00023752:_____/09:00001023 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Social interaction deficits in schizophrenia-spectrum disorders and pharmacologic intervention
Original language description
Disturbances of social interaction in people suffering from major psychiatric illnesses have attracted concerns from clinicians, researchers, and healthcare administrators, as these deficits are a major determinant of outcome for patients. Impaired social abilities in schizophrenia-spectrum disorders and autism are thought to be partly attributable to specific aspects of symptomatology, such as negative symptoms (blunt affect, social withdrawal, anhedonia) and disturbances of several domains of cognitive function, e.g. verbal memory, working memory, attention/vigilance, and information processing. We recently found that severity of social cognition deficits is correlated with decreased concentrations of essential polyunsaturated fatty acids in the erythrocyte membrane in subjects with schizophrenia. Psychotropic drugs acting on monoamine receptors, such as serotonin (5-HT)-5HT1A, and 5-HT2A receptors, have been shown to improve social behavior and cognitive function in rodents. For exa
Czech name
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Czech description
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Publication year
2009
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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