Prefrontal and anterior cingulate cortex neurons encode attentional targets even 4 when they do not apparently bias behavior

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F16%3A43915012" target="_blank" >RIV/00023752:_____/16:43915012 - isvavai.cz</a>

Result on the web

<a href="http://jn.physiology.org/content/116/2/796" target="_blank" >http://jn.physiology.org/content/116/2/796</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1152/jn.00027.2016" target="_blank" >10.1152/jn.00027.2016</a>

Result language

angličtina

Original language name

Prefrontal and anterior cingulate cortex neurons encode attentional targets even 4 when they do not apparently bias behavior

Original language description

Neurons in anterior cingulate and prefrontal cortex (ACC/PFC) carry information about behaviorally relevant target stimuli. This information is believed to affect behavior by exerting a top-down attentional bias on stimulus selection. However, attention information may not necessarily be a biasing signal, but could be a corollary signal that is not directly related to ongoing behavioral success, or it could reflect the monitoring of targets similar to an eligibility trace useful for later attentional adjustment. To test this suggestion we quantified how attention information relates to behavioral success in neurons recorded in multiple subfields in macaque ACC/PFC during a cued attention task. We found that attention cues activated three separable neuronal groups that encoded spatial attention information but were differently linked to behavioral success. A first group encoded attention targets on correct and error trials. This group spread across ACC/PFC and represented targets transiently after cue onset, irrespective of behavior. A second group encoded attention targets on correct trials only, closely predicting behavior. These neurons were not only prevalent in lateral prefrontal, but also in anterior cingulate cortex. A third group encoded target locations only on error trials. This group was evident in ACC and PFC and was activated in error trials 'as if' attention was shifted to the target location but without evidence for such behavior. These results show that only a portion of neuronaly available information about attention targets biases behavior. We speculate that additionally a unique neural subnetwork encodes counterfactual attention information.

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

—

Project

—

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Neurophysiology

ISSN

0022-3077

e-ISSN

—

Volume of the periodical

116

Issue of the periodical within the volume

2

Country of publishing house

US - UNITED STATES

Number of pages

16

Pages from-to

796-811

UT code for WoS article

000384246700009

EID of the result in the Scopus database

2-s2.0-84984623338