Subjective cognitive complaints in cognitively healthy older adults and their relation to cognitive performance and depressive symptoms

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F17%3A43915428" target="_blank" >RIV/00023752:_____/17:43915428 - isvavai.cz</a>

Result on the web

<a href="http://content.iospress.com/articles/journal-of-alzheimers-disease/jad160970" target="_blank" >http://content.iospress.com/articles/journal-of-alzheimers-disease/jad160970</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3233/JAD-160970" target="_blank" >10.3233/JAD-160970</a>

Result language

angličtina

Original language name

Subjective cognitive complaints in cognitively healthy older adults and their relation to cognitive performance and depressive symptoms

Original language description

Background: Subjective cognitive complaints (SCCs) may be an early marker of prodromal Alzheimer´s disease. Objectives: Using a 10-item yes/no SCCs questionnaire (Le Questionnaire de Plainte Cognitive [QPC]), we evaluated the prevalence and distribution of SCCs in cognitively healthy Czech older adults and examined total score and specific QPC items in relation to depressive symptomology and cognitive performance. Methods: A sample of 340 cognitively healthy older community-dwelling volunteers aged 60 or older from the third wave of the longitudinal project National Normative Study of Cognitive Determinants of Healthy Aging, who underwent a comprehensive neuropsychological assessment and completed the QPC and the 15-item Geriatric Depression Scale (GDS-15). Regression analysis was controlled for age when GDS-15 was the outcome and for age and GDS-15 with cognitive domains as the outcome. Results: Seventy-one percent reported 1+ SCCs, with prevalence of individual complaints ranging from 4% to 40%. The number of SCCs was associated with GDS-15 (p&lt;0.001). &quot;Personality change&quot; (p&lt;0.001) and &quot;Limitation in daily activities&quot; (p=0.002) were significantly associated with higher GDS-15 score and &quot;Spatial orientation difficulties&quot; (p=0.019) and &quot;Impression of worse memory in comparison to peers&quot; (p=0.012) were significantly associated with lower memory performance. Conclusions: We identified some cognitive complaints that were very common in our sample. Overall, a higher number of SCCs in well cognitively functioning individuals was most closely related to depressive symptomatology, while some specific complaints reflected lower memory performance and should be considered when screening for people at risk of cognitive decline.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30103 - Neurosciences (including psychophysiology)

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Alzheimer´s Disease

ISSN

1387-2877

e-ISSN

—

Volume of the periodical

59

Issue of the periodical within the volume

3

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

11

Pages from-to

871-881

UT code for WoS article

000406926700006

EID of the result in the Scopus database

2-s2.0-85026797050