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Latent schizencephaly with psychotic phenotype or schizophrenia with schizencephaly? a case report and review of the literature

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F18%3A43919403" target="_blank" >RIV/00023752:_____/18:43919403 - isvavai.cz</a>

  • Alternative codes found

    RIV/00023752:_____/19:43919403 RIV/00216208:11120/19:43916747 RIV/00023884:_____/19:00007992

  • Result on the web

    <a href="https://journals.sagepub.com/doi/10.1177/1550059418781119" target="_blank" >https://journals.sagepub.com/doi/10.1177/1550059418781119</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1177/1550059418781119" target="_blank" >10.1177/1550059418781119</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Latent schizencephaly with psychotic phenotype or schizophrenia with schizencephaly? a case report and review of the literature

  • Original language description

    Objectives. Although schizencephaly belongs to the class of neurodevelopmental disorders, which are a well-known predisposing factor for psychosis, there is a lack of relevant studies and diagnostic guidelines on this relationship. Method. A case report of first-episode psychosis with persistent negative symptoms associated with schizencephaly is described and compared with 7 other cases found in the literature. Results. We found perinatal pathology, cognitive deficit, and EEG abnormality in a patient with atypical initial symptoms of psychosis such as olfactory hallucinations. Abnormal EEG findings (left frontal spikes and frontal intermittent rhythmic delta activity) called for magnetic resonance imaging, which revealed left parieto-occipital closed-lip schizencephaly. The patient exhibited a partial response to low-dose amisulpride treatment. Conclusion. We conclude that schizencephaly in our patient was at first asymptomatic and later developed into clinically manifest schizophrenia-like disorder. Both magnetic resonance imaging and EEG were essential tools for establishing this diagnosis.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30215 - Psychiatry

Result continuities

  • Project

    <a href="/en/project/LO1611" target="_blank" >LO1611: Sustainability for The National Institute of Mental Health</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Clinical EEG and Neuroscience

  • ISSN

    1550-0594

  • e-ISSN

  • Volume of the periodical

    50

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    7

  • Pages from-to

    13-19

  • UT code for WoS article

    000453559100002

  • EID of the result in the Scopus database