Mortality in people with mental disorders in the Czech Republic: a nationwide, register-based cohort study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F18%3A43919430" target="_blank" >RIV/00023752:_____/18:43919430 - isvavai.cz</a>

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S246826671830077X?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S246826671830077X?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/S2468-2667(18)30077-X" target="_blank" >10.1016/S2468-2667(18)30077-X</a>

Result language

angličtina

Original language name

Mortality in people with mental disorders in the Czech Republic: a nationwide, register-based cohort study

Original language description

Background: The region of central and eastern Europe is estimated to have high rates of premature mortality due to mental disorders. However, epidemiological evidence is scarce and insufficient to inform policy actions and health system development. We aimed to assess mortality associated with mental disorders in the Czech Republic. Methods: We did a nationwide, register-based, retrospective cohort study using routinely collected health data from two nationwide registries in the Czech Republic: the register of inpatient discharges (from Jan 1, 1994, to Dec 31, 2013) and the causes of death registry (from Jan 1, 1994, to Dec 31, 2014). We first identified all individuals discharged from mental health institutions with WHO International Classification of Diseases tenth edition (ICD-10) diagnoses of mental and behavioural disorders (from 1994 to 2013). We then did a deterministic individual-level linkage of these data with all-cause mortality data for the whole period (1994–2014). Standardised mortality ratios (SMRs) and 95% CIs were calculated for the year 2014, comparing deaths in people with mental and behavioural disorders discharged from psychiatric hospitals with deaths in the general population. Findings: The final study population comprised 283 618 individuals. 3819 of these individuals died in 2014, corresponding to a mortality risk more than two times higher than that of the general population (SMR estimate 2·2; 95% CI 2·2–2·3). Differences in SMR estimates across diagnostic groups were substantial, with the highest SMR for substance use disorders (3·5; 95% CI 3·4–3·7) followed by schizophrenia, schizotypal, and delusional disorders (2·3; 2·1–2·5), personality disorders (2·3; 2·0–2·6), neurotic, stress-related, and somatoform disorders (1·8; 1·6–1·9), and mood (affective) disorders (1·6; 1·5–1·7). Interpretation: Mortality among people with mental disorders in the Czech Republic is markedly higher than in the general population. Our findings should stimulate and inform policy in the central and eastern Europe region, as well as ongoing national mental health-care reforms in the Czech Republic. Funding: Czech Ministry of Education, Youth and Sports.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30304 - Public and environmental health

Project

<a href="/en/project/LO1611" target="_blank" >LO1611: Sustainability for The National Institute of Mental Health</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

The Lancet Public Health

ISSN

2468-2667

e-ISSN

—

Volume of the periodical

3

Issue of the periodical within the volume

6

Country of publishing house

GB - UNITED KINGDOM

Number of pages

7

Pages from-to

"e289"-"e295"

UT code for WoS article

000437221800011

EID of the result in the Scopus database

2-s2.0-85048478663