Treatment of behavioral and psychological symptoms of dementias with psychopharmaceuticals: a review
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F18%3A43921505" target="_blank" >RIV/00023752:_____/18:43921505 - isvavai.cz</a>
Result on the web
<a href="https://www.dovepress.com/treatment-of-behavioral-and-psychological-symptoms-of-dementias-with-p-peer-reviewed-fulltext-article-NDT" target="_blank" >https://www.dovepress.com/treatment-of-behavioral-and-psychological-symptoms-of-dementias-with-p-peer-reviewed-fulltext-article-NDT</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2147/NDT.S163842" target="_blank" >10.2147/NDT.S163842</a>
Alternative languages
Result language
angličtina
Original language name
Treatment of behavioral and psychological symptoms of dementias with psychopharmaceuticals: a review
Original language description
Abstract: Behavioral and psychological symptoms represent common complications in patients with different types of dementia. Predominantly, they comprise psychosis, agitation and mood disorders, disinhibited behavior, impairment of the sleep and wakefulness rhythm, wandering, perseveration, pathological collecting, or shouting. Their appearance is related to more rapid progression of the disease, earlier institutionalization, use of physical restraints, and higher risk of mortality. Consequently, appearance of behavioral and psychological symptoms of dementia leads to higher costs of care provided and greater distress for caregivers. Clinical guidelines recommend nonpharmacological approaches as the first choice in the treatment of behavioral and psychological symptoms. Pharmacological therapy should be initiated only if the symptoms were not the result of somatic causes, did not respond to nonpharmacological interventions, or were not caused by the prior medication. Acetylcholinesterase inhibitors, memantine, antipsychotic drugs, antidepressants, mood stabilizers, and benzodiazepines are used. This review summarizes the current findings about the efficacy and safety of the treatment of the neuropsychiatric symptoms in dementias with psychopharmaceuticals. Recommendations for treatment with antipsychotics for this indication are described in detail as this drug group is prescribed most often and, at the same time, is related to the highest risk of adverse effects and increased mortality.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30215 - Psychiatry
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Neuropsychiatric Disease and Treatment
ISSN
1176-6328
e-ISSN
1178-2021
Volume of the periodical
2018
Issue of the periodical within the volume
14
Country of publishing house
GB - UNITED KINGDOM
Number of pages
10
Pages from-to
1211-1220
UT code for WoS article
000432040600003
EID of the result in the Scopus database
2-s2.0-85048730578