Latent toxoplasmosis and vitamin D concentration in humans: three observational studies

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F21%3A43920520" target="_blank" >RIV/00023752:_____/21:43920520 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11310/21:10423393 RIV/00216208:11120/21:43921140

Result on the web

<a href="https://folia.paru.cas.cz/artkey/fol-202101-0005_latent_toxoplasmosis_and_vitamin_d_concentration_in_humans_three_observational_studies.php" target="_blank" >https://folia.paru.cas.cz/artkey/fol-202101-0005_latent_toxoplasmosis_and_vitamin_d_concentration_in_humans_three_observational_studies.php</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.14411/fp.2021.005" target="_blank" >10.14411/fp.2021.005</a>

Result language

angličtina

Original language name

Latent toxoplasmosis and vitamin D concentration in humans: three observational studies

Original language description

Numerous recent studies show that vitamin D deficiency potentiates various chronic physical and psychiatric disorders and diseases. It has been shown that a similar range of disorders is also associated with latent infection with Toxoplasma gondii (Nicolle et Manceaux, 1908). For instance, among cancer, diabetes and schizophrenia patients, we find a higher prevalence of both toxoplasmosis and vitamin D deficiency. Theoretically, therefore, vitamin D deficiency could be the missing link between toxoplasmosis and these disorders. We tested this hypothesis by searching for decreased vitamin D levels in the serum of subjects infected with T. gondii (furthermore called Toxoplasma-infected subjects) in two cross-sectional and one case-control study. Results of the first cross-sectional study (N = 72) suggest that Toxoplasma-infected neurasthenic patients have non-significantly lower levels of calcidiol than Toxoplasma-free patients (study A: P = 0.26 in women, P = 0.68 in men). However, two other studies (study B: N = 400; study C: N = 191) showed a non-significantly higher concentration of vitamin D in Toxoplasma-infected subjects than in Toxoplasma-free subjects both in men (study B: P = 0.70, study C: P = 0.55) and in women (study B: P = 0.64, study C: P = 0.12). Taken together, our preliminary results thus do not support the hypothesis that toxoplasmosis could be associated with vitamin D decrease.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

Project

<a href="/en/project/GA18-13692S" target="_blank" >GA18-13692S: Conservation of Rh Polymorphism in Modern Humans through Selection Favoring Heterozygotes – The Influence of the Genotype on Fertility and Viability</a><br>

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Folia Parasitologica

ISSN

0015-5683

e-ISSN

—

Volume of the periodical

68

Issue of the periodical within the volume

"Article Number: 005"

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

7

Pages from-to

1-7

UT code for WoS article

000624331700001

EID of the result in the Scopus database

2-s2.0-85101784114