Real-time excitation of slow oscillations during deep sleep using acoustic stimulation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F21%3A43920638" target="_blank" >RIV/00023752:_____/21:43920638 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11120/21:43921829 RIV/68407700:21460/21:00350741
Result on the web
<a href="https://www.mdpi.com/1424-8220/21/15/5169" target="_blank" >https://www.mdpi.com/1424-8220/21/15/5169</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/s21155169" target="_blank" >10.3390/s21155169</a>
Alternative languages
Result language
angličtina
Original language name
Real-time excitation of slow oscillations during deep sleep using acoustic stimulation
Original language description
Slow-wave synchronous acoustic stimulation is a promising research and therapeutic tool. It is essential to clearly understand the principles of the synchronization methods, to know their performances and limitations, and, most importantly, to have a clear picture of the effect of stimulation on slow-wave activity (SWA). This paper covers the mentioned and currently missing parts of knowledge that are essential for the appropriate development of the method itself and future applications. Artificially streamed real sleep EEG data were used to quantitatively compare the two currently used real-time methods: the phase-locking loop (PLL) and the fixed-step stimulus in our own implementation. The fixed-step stimulation method was concluded to be more reliable and practically applicable compared to the PLL method. The sleep experiment with chronic insomnia patients in our sleep laboratory was analyzed in order to precisely characterize the effect of sound stimulation during deep sleep. We found that there is a significant phase synchronization of delta waves, which were shown to be the most sensitive metric of the effect of acoustic stimulation compared to commonly used averaged signal and power analyses. This finding may change the understanding of the effect and function of the SWA stimulation described in the literature.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30401 - Health-related biotechnology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Sensors
ISSN
1424-8220
e-ISSN
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Volume of the periodical
21
Issue of the periodical within the volume
15
Country of publishing house
CH - SWITZERLAND
Number of pages
26
Pages from-to
"Article Number: 5169"
UT code for WoS article
000682327100001
EID of the result in the Scopus database
2-s2.0-85111434868