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Real-time excitation of slow oscillations during deep sleep using acoustic stimulation

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F21%3A43920638" target="_blank" >RIV/00023752:_____/21:43920638 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11120/21:43921829 RIV/68407700:21460/21:00350741

  • Result on the web

    <a href="https://www.mdpi.com/1424-8220/21/15/5169" target="_blank" >https://www.mdpi.com/1424-8220/21/15/5169</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.3390/s21155169" target="_blank" >10.3390/s21155169</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Real-time excitation of slow oscillations during deep sleep using acoustic stimulation

  • Original language description

    Slow-wave synchronous acoustic stimulation is a promising research and therapeutic tool. It is essential to clearly understand the principles of the synchronization methods, to know their performances and limitations, and, most importantly, to have a clear picture of the effect of stimulation on slow-wave activity (SWA). This paper covers the mentioned and currently missing parts of knowledge that are essential for the appropriate development of the method itself and future applications. Artificially streamed real sleep EEG data were used to quantitatively compare the two currently used real-time methods: the phase-locking loop (PLL) and the fixed-step stimulus in our own implementation. The fixed-step stimulation method was concluded to be more reliable and practically applicable compared to the PLL method. The sleep experiment with chronic insomnia patients in our sleep laboratory was analyzed in order to precisely characterize the effect of sound stimulation during deep sleep. We found that there is a significant phase synchronization of delta waves, which were shown to be the most sensitive metric of the effect of acoustic stimulation compared to commonly used averaged signal and power analyses. This finding may change the understanding of the effect and function of the SWA stimulation described in the literature.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30401 - Health-related biotechnology

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Sensors

  • ISSN

    1424-8220

  • e-ISSN

  • Volume of the periodical

    21

  • Issue of the periodical within the volume

    15

  • Country of publishing house

    CH - SWITZERLAND

  • Number of pages

    26

  • Pages from-to

    "Article Number: 5169"

  • UT code for WoS article

    000682327100001

  • EID of the result in the Scopus database

    2-s2.0-85111434868