Psychopharmacological Agents During Pregnancy and Nursing
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F22%3A43920379" target="_blank" >RIV/00023752:_____/22:43920379 - isvavai.cz</a>
Result on the web
<a href="https://link.springer.com/referenceworkentry/10.1007/978-3-030-62059-2_268" target="_blank" >https://link.springer.com/referenceworkentry/10.1007/978-3-030-62059-2_268</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-3-319-56015-1_268-1" target="_blank" >10.1007/978-3-319-56015-1_268-1</a>
Alternative languages
Result language
angličtina
Original language name
Psychopharmacological Agents During Pregnancy and Nursing
Original language description
Decision-making about pharmacotherapy of mental disorders during pregnancy and lactation is a source of uncertainty in clinical practice. Potentially deleterious effects of drugs on the fetus and the infant are much feared; but at the same time, negative impact of untreated mental disorder have to be taken into account. Discontinuation of long-term medication increases greatly the risk of a relapse, may worsen the course of illness and result in poor overall outcome. Drug pharmacokinetics is markedly changed throughout the pregnancy and postpartum; thus, the dosage has to be adjusted appropriately. It should be emphasized that mental disorders alone have been associated with numerous pre-, peri- and postnatal complications and adverse effects on the fetus and the infant. Therefore, not all negative outcomes can be attributed to the medication. All psychotropic drugs cross placental barrier and pass into the maternal milk. The risk associated with drug treatment in pregnancy depends primarily on the period of exposure, gestational age. Teratogenic potential is greatest during the first trimester, neurobehavioral effects during the exposure in the last trimester, and withdrawal and intoxication with administration prior to the delivery. The chapter reviews available data on the risks and safety of antipsychotics, antidepressants, mood stabilizers, anxiolytics, hypnotics and other psychopharmacological agents in pregnancy and nursing.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
30215 - Psychiatry
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
NeuroPsychopharmacotherapy
ISBN
978-3-030-62058-5
Number of pages of the result
27
Pages from-to
4355-4381
Number of pages of the book
4784
Publisher name
Springer
Place of publication
Berlin
UT code for WoS chapter
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