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Psychopharmacological Agents During Pregnancy and Nursing

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F22%3A43920379" target="_blank" >RIV/00023752:_____/22:43920379 - isvavai.cz</a>

  • Result on the web

    <a href="https://link.springer.com/referenceworkentry/10.1007/978-3-030-62059-2_268" target="_blank" >https://link.springer.com/referenceworkentry/10.1007/978-3-030-62059-2_268</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/978-3-319-56015-1_268-1" target="_blank" >10.1007/978-3-319-56015-1_268-1</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Psychopharmacological Agents During Pregnancy and Nursing

  • Original language description

    Decision-making about pharmacotherapy of mental disorders during pregnancy and lactation is a source of uncertainty in clinical practice. Potentially deleterious effects of drugs on the fetus and the infant are much feared; but at the same time, negative impact of untreated mental disorder have to be taken into account. Discontinuation of long-term medication increases greatly the risk of a relapse, may worsen the course of illness and result in poor overall outcome. Drug pharmacokinetics is markedly changed throughout the pregnancy and postpartum; thus, the dosage has to be adjusted appropriately. It should be emphasized that mental disorders alone have been associated with numerous pre-, peri- and postnatal complications and adverse effects on the fetus and the infant. Therefore, not all negative outcomes can be attributed to the medication. All psychotropic drugs cross placental barrier and pass into the maternal milk. The risk associated with drug treatment in pregnancy depends primarily on the period of exposure, gestational age. Teratogenic potential is greatest during the first trimester, neurobehavioral effects during the exposure in the last trimester, and withdrawal and intoxication with administration prior to the delivery. The chapter reviews available data on the risks and safety of antipsychotics, antidepressants, mood stabilizers, anxiolytics, hypnotics and other psychopharmacological agents in pregnancy and nursing.

  • Czech name

  • Czech description

Classification

  • Type

    C - Chapter in a specialist book

  • CEP classification

  • OECD FORD branch

    30215 - Psychiatry

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2022

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Book/collection name

    NeuroPsychopharmacotherapy

  • ISBN

    978-3-030-62058-5

  • Number of pages of the result

    27

  • Pages from-to

    4355-4381

  • Number of pages of the book

    4784

  • Publisher name

    Springer

  • Place of publication

    Berlin

  • UT code for WoS chapter