The potential of biomarkers for diagnosing insomnia: Consensus statement of the WFSBP Task Force on Sleep Disorders
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F23%3A43921078" target="_blank" >RIV/00023752:_____/23:43921078 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11120/23:43925241
Result on the web
<a href="https://www.tandfonline.com/doi/full/10.1080/15622975.2023.2171479" target="_blank" >https://www.tandfonline.com/doi/full/10.1080/15622975.2023.2171479</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/15622975.2023.2171479" target="_blank" >10.1080/15622975.2023.2171479</a>
Alternative languages
Result language
angličtina
Original language name
The potential of biomarkers for diagnosing insomnia: Consensus statement of the WFSBP Task Force on Sleep Disorders
Original language description
ObjectivesThus far, the diagnosis of insomnia is based on purely clinical criteria. Although a broad range of altered physiological parameters has been identified in insomniacs, the evidence to establish their diagnostic usefulness is very limited. Purpose of this WFSBP Task Force consensus paper is to systematically evaluate a series of biomarkers as potential diagnostic tools for insomnia.MethodsA newly created grading system was used for assessing the validity of various measurements in establishing the diagnosis of insomnia; these measurements originated from relevant studies selected and reviewed by experts.ResultsThe measurements with the highest diagnostic performance were those derived from psychometric instruments. Biological measurements which emerged as potentially useful diagnostic instruments were polysomnography-derived cyclic alternating pattern, actigraphy, and BDNF levels, followed by heart rate around sleep onset, deficient melatonin rhythm, and certain neuroimaging patterns (mainly for the activity of frontal and pre-frontal cortex, hippocampus and basal ganglia); yet, these findings need replication, as well as establishment of commonly accepted methodology and diagnostic cut-off points. Routine polysomnography, EEG spectral analysis, heart rate variability, skin conductance, thermoregulation, oxygen consumption, HPA axis, and inflammation indices were not shown to be of satisfactory diagnostic value.ConclusionsApart from psychometric instruments which are confirmed to be the gold standard in diagnosing insomnia, six biomarkers emerge as being potentially useful for this purpose.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30215 - Psychiatry
Result continuities
Project
—
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
World Journal of Biological Psychiatry
ISSN
1562-2975
e-ISSN
1814-1412
Volume of the periodical
24
Issue of the periodical within the volume
8
Country of publishing house
GB - UNITED KINGDOM
Number of pages
29
Pages from-to
614-642
UT code for WoS article
000945810800001
EID of the result in the Scopus database
2-s2.0-85150472326