Idiopathic hypersomnia years after the diagnosis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F24%3A43921145" target="_blank" >RIV/00023752:_____/24:43921145 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/24:10466535 RIV/00216208:11120/24:43925934 RIV/00064165:_____/24:10466535

Result on the web

<a href="https://onlinelibrary.wiley.com/doi/10.1111/jsr.14011" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1111/jsr.14011</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/jsr.14011" target="_blank" >10.1111/jsr.14011</a>

Result language

angličtina

Original language name

Idiopathic hypersomnia years after the diagnosis

Original language description

Little attention has been paid to the long-term development of idiopathic hypersomnia symptoms and idiopathic hypersomnia comorbidities. The aim of this study was to describe the general health of patients with idiopathic hypersomnia years after the initial diagnosis, focusing on current subjective hypersomnolence and the presence of its other possible causes. Adult patients diagnosed with idiopathic hypersomnia &amp; GE; 3 years ago at sleep centres in Prague and Kosice were invited to participate in this study. A total of 60 patients were examined (age 47.3 &amp; PLUSMN; SD = 13.2 years, 66.7% women). In all participants, their hypersomnolence could not be explained by any other cause but idiopathic hypersomnia at the time of diagnosis. The mean duration of follow-up was 9.8 + 8.0 years. Fifty patients (83%) reported persisting hypersomnolence, but only 33 (55%) had no other disease that could also explain the patient&apos;s excessive daytime sleepiness and/or prolonged sleep. In two patients (3%), the diagnosis in the meantime had changed to narcolepsy type 2, and 15 patients (25%) had developed a disease or diseases potentially causing hypersomnolence since the initial diagnosis. Complete hypersomnolence resolution without stimulant treatment lasting longer than 6 months was reported by 10 patients (17%). To conclude, in a longer interval from the diagnosis of idiopathic hypersomnia, hypersomnolence may disappear or may theoretically be explained by another newly developed disease, or the diagnosis may be changed to narcolepsy type 2. Thus, after 9.8 years, only 55% of the examined patients with idiopathic hypersomnia had a typical clinical picture of idiopathic hypersomnia without doubts about the cause of the current hypersomnolence.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30103 - Neurosciences (including psychophysiology)

Project

<a href="/en/project/NU20-04-00088" target="_blank" >NU20-04-00088: Gut microbiome and autoimmune mechanisms in patients with central hypersomnia</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Sleep Research

ISSN

0962-1105

e-ISSN

1365-2869

Volume of the periodical

33

Issue of the periodical within the volume

2

Country of publishing house

US - UNITED STATES

Number of pages

10

Pages from-to

"e14011"

UT code for WoS article

001046213600001

EID of the result in the Scopus database

2-s2.0-85167665724