The Gaze of Schizophrenia Patients Captured by Bottom-up Saliency
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F24%3A43921360" target="_blank" >RIV/00023752:_____/24:43921360 - isvavai.cz</a>
Alternative codes found
RIV/67985807:_____/24:00585040 RIV/68407700:21230/24:00372608 RIV/00216224:14210/24:00138255 RIV/00216208:11110/24:10477757 and 2 more
Result on the web
<a href="https://www.nature.com/articles/s41537-024-00438-4" target="_blank" >https://www.nature.com/articles/s41537-024-00438-4</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/s41537-024-00438-4" target="_blank" >10.1038/s41537-024-00438-4</a>
Alternative languages
Result language
angličtina
Original language name
The Gaze of Schizophrenia Patients Captured by Bottom-up Saliency
Original language description
Schizophrenia (SCHZ) notably impacts various human perceptual modalities, including vision. Prior research has identified marked abnormalities in perceptual organization in SCHZ, predominantly attributed to deficits in bottom-up processing. Our study introduces a novel paradigm to differentiate the roles of top-down and bottom-up processes in visual perception in SCHZ. We analysed eye-tracking fixation ground truth maps from 28 SCHZ patients and 25 healthy controls (HC), comparing these with two mathematical models of visual saliency: one bottom-up, based on the physical attributes of images, and the other top-down, incorporating machine learning. While the bottom-up (GBVS) model revealed no significant overall differences between groups (beta = 0.01, p = 0.281, with a marginal increase in SCHZ patients), it did show enhanced performance by SCHZ patients with highly salient images. Conversely, the top-down (EML-Net) model indicated no general group difference (beta = -0.03, p = 0.206, lower in SCHZ patients) but highlighted significantly reduced performance in SCHZ patients for images depicting social interactions (beta = -0.06, p < 0.001). Over time, the disparity between the groups diminished for both models. The previously reported bottom-up bias in SCHZ patients was apparent only during the initial stages of visual exploration and corresponded with progressively shorter fixation durations in this group. Our research proposes an innovative approach to understanding early visual information processing in SCHZ patients, shedding light on the interplay between bottom-up perception and top-down cognition.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30215 - Psychiatry
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Schizophrenia
ISSN
2754-6993
e-ISSN
2754-6993
Volume of the periodical
10
Issue of the periodical within the volume
1
Country of publishing house
DE - GERMANY
Number of pages
13
Pages from-to
"Article number 21"
UT code for WoS article
001228839900001
EID of the result in the Scopus database
2-s2.0-85185510655