Effects of in vitro fertilization and intracytoplasmic sperm injection treatment on female patients' perinatal mental health: systematic review and meta-analysis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F25%3A43921658" target="_blank" >RIV/00023752:_____/25:43921658 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/25:10503887 RIV/00216208:11120/25:43928951 RIV/00216208:11130/25:10503887 RIV/00216208:11210/25:10503887 RIV/00216208:11310/25:10503887
Result on the web
<a href="https://www.frontiersin.org/journals/reproductive-health/articles/10.3389/frph.2025.1668831/full" target="_blank" >https://www.frontiersin.org/journals/reproductive-health/articles/10.3389/frph.2025.1668831/full</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3389/frph.2025.1668831" target="_blank" >10.3389/frph.2025.1668831</a>
Alternative languages
Result language
angličtina
Original language name
Effects of in vitro fertilization and intracytoplasmic sperm injection treatment on female patients' perinatal mental health: systematic review and meta-analysis
Original language description
Introduction: In vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) patients often experience stress, which exacerbates the burden associated with infertility and may lead to an increased risk of mental-health difficulties. In this systematic review and meta-analysis, we examined the effects of IVF or ICSI on female patients' mental health. Methods: A database search was conducted in PubMed, Web of Science, and PsychInfo to select relevant studies. Forty-four studies involving 858,966 participants were included in the systematic review. The results of these studies were very heterogeneous and yielded contradictory findings. Two meta-analyses, comprising a total of seven studies, were conducted. The first calculated the standardized mean difference of symptoms of depression between women who became pregnant through IVF and those who conceived spontaneously. In the second, we compared symptoms of anxiety between these two groups. Results: Five studies examined depressive symptoms and showed no significant difference between the two groups: SMD = -.15; 95% CI [-.33,.03], p = .10. A meta-analysis of six studies on anxiety symptoms revealed significantly higher levels in the IVF groups compared to the controls: SMD = .33; 95% CI [.17,.49], p < .001. Discussion: The results suggest that the psychological effects of IVF/ICSI, especially with respect to anxiety, require attention and support from healthcare providers, although the effect size is small. Further studies with adequate sample sizes, including women with both successful and unsuccessful treatment, and adequately controlling for important confounders are needed to fully understand the effects of IVF/ICSI on mental health.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30304 - Public and environmental health
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Frontiers in Reproductive Health
ISSN
2673-3153
e-ISSN
2673-3153
Volume of the periodical
7
Issue of the periodical within the volume
"Article Number 1668831"
Country of publishing house
CH - SWITZERLAND
Number of pages
23
Pages from-to
1-23
UT code for WoS article
001588883600001
EID of the result in the Scopus database
2-s2.0-105018723053