Intracellular calcium level in blood platelets during normal and pathological aging and the effect of aluminofluoride complexes.

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F99%3A00000018" target="_blank" >RIV/00023752:_____/99:00000018 - isvavai.cz</a>
Result on the web
—
DOI - Digital Object Identifier
—

Result language
angličtina
Original language name
Intracellular calcium level in blood platelets during normal and pathological aging and the effect of aluminofluoride complexes.
Original language description
The platelet free intracellular calcium level ([Ca2+]i) was measured in patients suffering from Alzheimer`s disease (AD), age-matched and young control groups in this study. Also the influence of AlF4- on the [Ca2+]i in all these groups was tested between young and old control healthy subjects. The [Ca2+]i was significantly lower in AD patients than in age-matched and young controls. AlF4- reduces [Ca2+]i in young control group to 85.8+-2.9%, in age-matched control group to 90.2+-2.7% and in AD patientsto 98.5+-3.4% of unstimulated value. There was significant difference between the young controls and AD patients. From these results we can conclude, that the [Ca2+]i is lower in AD patients as compared to age-matched and young healthy controls. AlF4- did not affect the [Ca2+]i in platelets of AD patients.
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
—

Project
<a href="/en/project/NG15" target="_blank" >NG15: Biomarkers of Alzheimer's disease.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
1999
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)