Endocrine Risk Factors for COVID-19 in Context of Aging
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023761%3A_____%2F21%3AN0000036" target="_blank" >RIV/00023761:_____/21:N0000036 - isvavai.cz</a>
Result on the web
<a href="https://www.biomed.cas.cz/physiolres/pdf/2021/70_S153.pdf" target="_blank" >https://www.biomed.cas.cz/physiolres/pdf/2021/70_S153.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.33549/physiolres.934723" target="_blank" >10.33549/physiolres.934723</a>
Alternative languages
Result language
angličtina
Original language name
Endocrine Risk Factors for COVID-19 in Context of Aging
Original language description
Aged people are the most susceptible group to COVID-19 infection. Immunosenescence characterized by impairment of immune function with inflamm-aging contributes to pathophysiological alterations, among which endocrine and metabolic diseases are not exception. Diabetes, obesity along with impairment of disorders of thyroid functions are the most frequent ones, the common feature of which is failure of immune system including autoimmune processes. In the minireview we discussed how COVID-19 and aging impact innate and adaptive immunity, diabetes and selected neuroendocrine processes. Mentioned is also beneficial effect of vitamin D for attenuation of these diseases and related epigenetic issues. Particular attention is devoted to the role of ACE2 protein in the light of its intimate link with renin-angiotensin regulating system.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30105 - Physiology (including cytology)
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
PHYSIOLOGICAL RESEARCH
ISSN
0862-8408
e-ISSN
1802-9973
Volume of the periodical
70
Issue of the periodical within the volume
Supplement 2
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
7
Pages from-to
„S-153“- „S-159“
UT code for WoS article
000740730700006
EID of the result in the Scopus database
2-s2.0-85122843276