Disgust sensitivity is negatively associated with immune system activity in early pregnancy: Direct support for the Compensatory Prophylaxis Hypothesis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023761%3A_____%2F22%3AN0000004" target="_blank" >RIV/00023761:_____/22:N0000004 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11310/22:10444116 RIV/00216208:11210/22:10444116
Result on the web
<a href="https://www.sciencedirect.com/science/article/abs/pii/S1090513822000058" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S1090513822000058</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.evolhumbehav.2022.02.001" target="_blank" >10.1016/j.evolhumbehav.2022.02.001</a>
Alternative languages
Result language
angličtina
Original language name
Disgust sensitivity is negatively associated with immune system activity in early pregnancy: Direct support for the Compensatory Prophylaxis Hypothesis
Original language description
According to the Compensatory Prophylaxis Hypothesis (CPH), disgust may be considered a part of the behavioral immune system, adjusting as a function of immunocompetence. Early pregnancy involves modulation of a complex network of various immune-related factors, but only a few studies so far have focused on disgust sensitivity in pregnant women in the context of the CPH. This study aimed to examine associations between disgust sensitivity and immune activity indices, cytokine levels, and white blood cell (WBC) count in pregnant women. The sample included 78 women in the 1st trimester of pregnancy. Higher disgust sensitivity (Disgust Scale-Revised; DS-R) was significantly associated with decreased levels of IL-1(i, IL-2 IL-4, IL-7, IL-17, Eotaxin, MCP-1 (MCAF), and RANTES in blood serum. This model explained 17.5% of the total DS-R score variability. Using the DS-R subscales, the Contamination disgust was significantly associated with levels of FGF basic, IFN-gamma, IL-1(i, IL-2, IL-4, IL-7, IL-17A, G-CSF, MCP-1 (MCAF), MIP-1 alpha, PDGF-BB, and RANTES, and the Core disgust was significantly associated with levels of IL-1(i, IL-2, IL-4, IL-7, IL-17A, Eotaxin, G-CSF, IP-10, MCP-1 (MCAF), PDGFBB, and TNF-alpha. Disgust sensitivity was not associated with WBC count. Disgust may reflect and compensate for insufficient immune adaptation in early pregnancy, suggesting the potential clinical significance of this common prenatal symptom.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10614 - Behavioral sciences biology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
EVOLUTION AND HUMAN BEHAVIOR
ISSN
1090-5138
e-ISSN
1879-0607
Volume of the periodical
43
Issue of the periodical within the volume
3
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
234-241
UT code for WoS article
000797243400007
EID of the result in the Scopus database
2-s2.0-85125362217