Progesterone: A Steroid with Wide Range of Effects in Physiology as Well as Human Medicine

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023761%3A_____%2F22%3AN0000005" target="_blank" >RIV/00023761:_____/22:N0000005 - isvavai.cz</a>
Alternative codes found
RIV/00064165:_____/22:10445738 RIV/00216208:11110/22:10445738
Result on the web
<a href="https://www.mdpi.com/1422-0067/23/14/7989" target="_blank" >https://www.mdpi.com/1422-0067/23/14/7989</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/ijms23147989" target="_blank" >10.3390/ijms23147989</a>

Result language
angličtina
Original language name
Progesterone: A Steroid with Wide Range of Effects in Physiology as Well as Human Medicine
Original language description
Progesterone is a steroid hormone traditionally linked with female fertility and pregnancy. In current reproductive medicine, progesterone and its analogues play crucial roles. While the discovery of its effects has a long history, over recent decades, various novel actions of this interesting steroid have been documented, of which its neuro- and immunoprotective activities are the most widely discussed. Discoveries of the novel biological activities of progesterone have also driven research and development in the field of progesterone analogues used in human medicine. Progestogen treatment has traditionally and predominately been used in maintaining pregnancy, the prevention of preterm labor, various gynecological pathologies, and in lowering the negative effects of menopause. However, there are also various other medical fields where progesterone and its analogues could find application in the future. The aim of this work is to show the mechanisms of action of progesterone and its metabolites, the physiological and pharmacological actions of progesterone and its synthetic analogues in human medicine, as well as the impacts of its production and use on the environment.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30107 - Medicinal chemistry

Project
<a href="/en/project/NU21J-01-00040" target="_blank" >NU21J-01-00040: Intraprostatic steroids: the role of alternative biosynthetic pathways and exposure to endocrine disruptors in the development of prostate cancer</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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