COVID-19, Vaccination, and Female Fertility in the Czech Republic
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023761%3A_____%2F22%3AN0000006" target="_blank" >RIV/00023761:_____/22:N0000006 - isvavai.cz</a>
Alternative codes found
RIV/00064165:_____/22:10448100 RIV/00216208:11110/22:10448100
Result on the web
<a href="https://www.mdpi.com/1422-0067/23/18/10909" target="_blank" >https://www.mdpi.com/1422-0067/23/18/10909</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/ijms231810909" target="_blank" >10.3390/ijms231810909</a>
Alternative languages
Result language
angličtina
Original language name
COVID-19, Vaccination, and Female Fertility in the Czech Republic
Original language description
The fast-track process to approve vaccines against COVID-19 has raised questions about their safety, especially in relation to fertility. Over the last 2 years, studies have appeared monitoring female fertility, especially from assisted reproduction centers or in animal experiments. However, studies monitoring healthy populations are still limited. The aim of our study was to monitor the relevant parameters of female fertility (sex and other steroids, LH, FSH, SHBG, Antimullerian hormone and antral follicle count) before and then 2-4 months after the third dose of vaccination against COVID-19 in a group of 25 healthy fertile woman. In addition, anti-SARS-CoV-2 and anti-SARS-CoV-2S antibodies were determined. We did not observe significant changes in the measured parameters before and after the third dose of vaccination. By comparing levels of the analytes with antibodies indicating a prior COVID-19 infection, we found that women who had experienced the disease had statistically lower levels of estrone, estradiol, SHBG and 5 alpha-dihydroprogesterone, and conversely, higher levels of androgen active dehydroepiandrosterone and dihydrotestosterone. Our results confirm that vaccination does not affect female fertility, and that what fertile women should be worried about is not vaccination, but rather COVID-19 infection itself.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30107 - Medicinal chemistry
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International Journal of Molecular Sciences
ISSN
1422-0067
e-ISSN
1422-0067
Volume of the periodical
23
Issue of the periodical within the volume
18
Country of publishing house
CH - SWITZERLAND
Number of pages
16
Pages from-to
Article Number 10909
UT code for WoS article
000856379700001
EID of the result in the Scopus database
2-s2.0-85138338412