Dietary protein and the glycemic index handle insulin resistance within a nutritional program for avoiding weight regain after energy-restricted induced weight loss
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023761%3A_____%2F22%3AN0000013" target="_blank" >RIV/00023761:_____/22:N0000013 - isvavai.cz</a>
Result on the web
<a href="https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/s12986-022-00707-y" target="_blank" >https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/s12986-022-00707-y</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1186/s12986-022-00707-y" target="_blank" >10.1186/s12986-022-00707-y</a>
Alternative languages
Result language
angličtina
Original language name
Dietary protein and the glycemic index handle insulin resistance within a nutritional program for avoiding weight regain after energy-restricted induced weight loss
Original language description
The role of dietary protein and glycemic index on insulin resistance (based on TyG index) within a nutritional program for weight loss and weight maintenance was examined. Methods This study analyzed 744 adults with overweight/obesity within the DIOGenes project. Patients who lost at least 8% of their initial weight (0-8 weeks) after a low-calorie diet (LCD) were randomly assigned to one of five ad libitum diets designed for weight maintenance (8-34 weeks): high/low protein (HP/LP) and high/low glycemic index (HGI/LGI), plus a control. The complete nutritional program (0-34 weeks) included both LCD plus the randomized diets intervention. The TyG index was tested as marker of body mass composition and insulin resistance. Results In comparison with the LP/HGI diet, the HP/LGI diet induced a greater BMI loss (p < 0.05). increment TyG was positively associated with resistance to BMI loss (beta = 0.343, p = 0.042) during the weight maintenance stage. In patients who followed the HP/LGI diet, TyG (after LCD) correlated with greater BMI loss in the 8-34 weeks period (r = -0.256; p < 0.05) and during the 0-34 weeks intervention (r = -0.222, p < 0.05) periods. Delta TyG(1) value was associated with Delta BMI2 (beta = 0.932; p = 0.045) concerning the HP/LGI diet. Conclusions A HP/LGI diet is beneficial not only for weight maintenance after a LCD, but is also related to IR amelioration as assessed by TyG index changes. Registration Clinical Trials NCT00390637.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30308 - Nutrition, Dietetics
Result continuities
Project
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Continuities
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Nutrition and Metabolism
ISSN
1743-7075
e-ISSN
1743-7075
Volume of the periodical
19
Issue of the periodical within the volume
1
Country of publishing house
GB - UNITED KINGDOM
Number of pages
15
Pages from-to
Article Number 71
UT code for WoS article
000870245500001
EID of the result in the Scopus database
2-s2.0-85140215823