Positive Antithyroid Antibodies and Nonsuppressed TSH Are Associated with Thyroid Cancer: A Retrospective Cross-Sectional Study

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023884%3A_____%2F18%3A00007928" target="_blank" >RIV/00023884:_____/18:00007928 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1155/2018/9793850" target="_blank" >http://dx.doi.org/10.1155/2018/9793850</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1155/2018/9793850" target="_blank" >10.1155/2018/9793850</a>

Result language
angličtina
Original language name
Positive Antithyroid Antibodies and Nonsuppressed TSH Are Associated with Thyroid Cancer: A Retrospective Cross-Sectional Study
Original language description
Thyroid cancer (TC) is the most common endocrine malignancy. Although it is still a rare disease, its incidence is growing rapidly in the last years, with approximately 14.3 new cases per 100,000 per year. The most frequent histomorphological type is papillary thyroid cancer (PTC), which represents 84% of thyroid malignancies [2]. Despite extensive research, TC pathogenesis remains largely unclear with the relationship between TC and Hashimoto thyroiditis (HT) being a frequently discussed issue. HT is one of the most common autoimmune diseases, with an estimated frequency of 5–10% and with females affected 5x more likely than males are. HT is characterized by T-lymphocyte infiltration of the thyroid gland, destruction of thyroid follicles, and their replacement by fibrotic tissue.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30204 - Oncology

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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