Acute effect of spinal cord stimulation on autonomic nervous system function in patients with heart failure
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023884%3A_____%2F21%3A00008953" target="_blank" >RIV/00023884:_____/21:00008953 - isvavai.cz</a>
Result on the web
<a href="https://jab.zsf.jcu.cz/artkey/jab-202103-0002_acute-effect-of-spinal-cord-stimulation-on-autonomic-nervous-system-function-in-patients-with-heart-failure.php" target="_blank" >https://jab.zsf.jcu.cz/artkey/jab-202103-0002_acute-effect-of-spinal-cord-stimulation-on-autonomic-nervous-system-function-in-patients-with-heart-failure.php</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.32725/jab.2021.012" target="_blank" >10.32725/jab.2021.012</a>
Alternative languages
Result language
angličtina
Original language name
Acute effect of spinal cord stimulation on autonomic nervous system function in patients with heart failure
Original language description
Aims: To test the hypothesis that spinal cord stimulation (SCS) acutely improves heart rate variability (HRV) and baroreceptor sensitivity (BRS) in patients with heart failure (HF). Methods: SCS (15 minutes) was delivered in four different settings: 90% of maximal tolerated stimulation amplitude (MTA) targeting the T1–T4 spinal cord segments (SCS90T1–4), 60% of MTA (SCS60T1–4), 90% of MTA with cranial (SCS90CR) and caudal (SCS90CA) electrode configuration. HRV and BRS were recorded continuously and stimulation was compared to device off. Results: Fifteen HF patients were included. SCS90T1–4 did not change the standard deviation of intervals between normal beats (SDNN, p = 0.90), BRS (p = 0.55) or other HRV parameters. In patients with baseline SDNN <50 ms, SCS90T1–4 significantly increased SDNN (p = 0.004). Conclusions: Acute SCS at 60–90% of MTA targeting upper thoracic spinal cord segments does not improve autonomic balance or baroreceptor sensitivity in unselected patients with heart failure but may improve HRV in patients with low SDNN.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal Of Applied Biomedicine
ISSN
1214-021X
e-ISSN
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Volume of the periodical
19
Issue of the periodical within the volume
3
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
133-141
UT code for WoS article
000705337500002
EID of the result in the Scopus database
2-s2.0-85115743978