Stereotactic Radiosurgery for Meningiomas in Children and Adolescents: An International Multi-Institutional Study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023884%3A_____%2F23%3A00009699" target="_blank" >RIV/00023884:_____/23:00009699 - isvavai.cz</a>
Result on the web
<a href="https://journals.lww.com/neurosurgery/fulltext/2023/11000/stereotactic_radiosurgery_for_meningiomas_in.14.aspx" target="_blank" >https://journals.lww.com/neurosurgery/fulltext/2023/11000/stereotactic_radiosurgery_for_meningiomas_in.14.aspx</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1227/neu.0000000000002543" target="_blank" >10.1227/neu.0000000000002543</a>
Alternative languages
Result language
angličtina
Original language name
Stereotactic Radiosurgery for Meningiomas in Children and Adolescents: An International Multi-Institutional Study
Original language description
BACKGROUND AND OBJECTIVES: Meningiomas in children are uncommon, with distinct characteristics that set them apart from their adult counterparts. The existing evidence for stereotactic radiosurgery (SRS) in this patient population is limited to only case series. The objective of this study was to evaluate the safety and efficacy of SRS in managing pediatric meningiomas.METHODS: Children and adolescents who had been treated for meningioma with single-fraction SRS were included in this retrospective, multicenter study. The assessment included local tumor control, any complications related to the tumor or SRS, and the emergence of new neurological deficits after SRS.RESULTS: The cohort included 57 patients (male-to-female ratio 1.6:1) with a mean age of 14.4 years who were managed with single-fraction SRS for 78 meningiomas. The median radiological and clinical follow-up periods were 69 months (range, 6-268) and 71 months (range, 6-268), respectively. At the last follow-up, tumor control (tumor stability and regression) was achieved in 69 (85.9%) tumors. Post-SRS, new neurological deficits occurred in 2 (3.5%) patients. Adverse radiation effects occurred in 5 (8.8%) patients. A de novo aneurysm was observed in a patient 69 months after SRS.CONCLUSION: SRS seems to be a safe and effective up-front or adjuvant treatment option for surgically inaccessible, recurrent, or residual pediatric meningiomas.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30210 - Clinical neurology
Result continuities
Project
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Continuities
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Neurosurgery
ISSN
0148-396X
e-ISSN
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Volume of the periodical
93
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
1066-1074
UT code for WoS article
001087785100027
EID of the result in the Scopus database
2-s2.0-85176304653