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Ormond's Disease - 26 Years of Experience at One Centre

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023884%3A_____%2F25%3A00010048" target="_blank" >RIV/00023884:_____/25:00010048 - isvavai.cz</a>

  • Alternative codes found

    RIV/00023001:_____/25:00085487

  • Result on the web

    <a href="https://www.medvik.cz/bmc/view.do?gid=2287022" target="_blank" >https://www.medvik.cz/bmc/view.do?gid=2287022</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.14712/23362936.2025.1" target="_blank" >10.14712/23362936.2025.1</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Ormond's Disease - 26 Years of Experience at One Centre

  • Original language description

    Ormond’s disease is a systemic autoimmune disease with serious complications. We present our retrospective analysis of 83 patients diagnosed with and treated for idiopathic retroperitoneal fibrosis (Ormond’s disease) in our department from 1997 to 2023. In this retrospective study, we analysed the diagnostic approaches, the clinical history and surgical and immunosuppressive therapies, and their subsequent effects on our patients. Patients with established disease activity were given immunosuppressive treatment, using corticosteroids alone or in combination with azathioprine, in patients with exacerbation of the disease mycophenolate mofetil. Three patients with Ormond’s disease and systemic complications (IgG4-related disease) were treated with rituximab. In the entire cohort, 83 patients received immunosuppressive therapy; the next 5 patients did not receive this treatment because they did not present inflammatory activity from the disease. In these 83 patients, computed tomography showed that immunosuppressive treatment resulted in partial or complete regression of the inflammatory infiltrate. Out of the 83 patients, 10 patient experienced disease exacerbation 7 and 24 months after the immunosuppressive treatment was discontinued. The follow-up ranged from 24 months to 26 years.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database

  • CEP classification

  • OECD FORD branch

    30102 - Immunology

Result continuities

  • Project

  • Continuities

    N - Vyzkumna aktivita podporovana z neverejnych zdroju

Others

  • Publication year

    2025

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Prague Medical Report

  • ISSN

    1214-6994

  • e-ISSN

  • Volume of the periodical

    126

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    6

  • Pages from-to

    3-8

  • UT code for WoS article

  • EID of the result in the Scopus database

    2-s2.0-86000206467