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In vitro and in vivo inhibition of -amylases of stored-product mite Acarus siro

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027006%3A_____%2F04%3A00013911" target="_blank" >RIV/00027006:_____/04:00013911 - isvavai.cz</a>

  • Alternative codes found

    RIV/00027006:_____/05:2845

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    In vitro and in vivo inhibition of -amylases of stored-product mite Acarus siro

  • Original language description

    Novel acaricidal compounds with inhibitory effects on the digestive enzymes of arthropods are a safe alternative to the traditional neurotoxic pesticides used for control of the stored-product pests. In this work, we explored the properties of acarbose,the low molecular weight inhibitor of -amylases (AI), as a novel acaricide candidate for protection of the stored products from infestation by Acarus siro (Acari: Acaridae). In vitro analysis revealed that AI blocked efficiently the enzymatic activity ofdigestive amylases of A. siro, and decreased the physiological capacity of mites gut in utilizing a starch component of grain flour. In vivo experiments showed that AI suppressed the population growth of A. siro. The mites were kept for three weeks on experimental diet enriched by AI in concentration range of 0.005 to 0.25%. Population growth of A. siro was negatively correlated with the content of AI in the treated diet with a half-population dose of 0.125%. The suppressive effect of A

  • Czech name

    In vitro a in vivo inhibice amylázy skladištního roztoče Acarus siro.

  • Czech description

    Nízkomolekulární inhbitor akarbóza inhubuje in vitro amylázu skladištního roztoče Acarus siro. Tato inhibice se in vivo projeví blokováním využití škrobu jako potravního zdroje pro tento druh roztoče. Takto ovlivnění roztoči se pomaleji množí, rychlost jejich populačního růstu závisí na koncentraci použitého inhibitoru.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    GF - Diseases, pests, weeds and plant protection

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/OC%20842.20" target="_blank" >OC 842.20: new method of control of stored product pests by synergic effect of natural enemies and inhibitors of digestive enzymes.</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2005

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Experimental and applied acarology

  • ISSN

    0168-8162

  • e-ISSN

  • Volume of the periodical

    4

  • Issue of the periodical within the volume

    35

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    11

  • Pages from-to

    281-291

  • UT code for WoS article

  • EID of the result in the Scopus database