Rationale for developing novel mosquito larvicides based on isofuranodiene microemulsions
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027006%3A_____%2F19%3A00005394" target="_blank" >RIV/00027006:_____/19:00005394 - isvavai.cz</a>
Alternative codes found
RIV/60460709:41210/19:80952
Result on the web
<a href="https://link.springer.com/content/pdf/10.1007/s10340-018-01076-3" target="_blank" >https://link.springer.com/content/pdf/10.1007/s10340-018-01076-3</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s10340-018-01076-3" target="_blank" >10.1007/s10340-018-01076-3</a>
Alternative languages
Result language
angličtina
Original language name
Rationale for developing novel mosquito larvicides based on isofuranodiene microemulsions
Original language description
Isofuranodiene is a bioactive furanosesquiterpene occurring as the major volatile compound in the essential oil from Smyrnium olusatrum (Apiaceae). It has a notable potentiality to be used as a botanical insecticide. However, its low solubility together with susceptibility to oxidation and thermal degradation limits its application on a wide scale. To face these challenges, isofuranodiene was encapsulated in stable microemulsions (MEs) at two concentrations (ME 750: 0.75%, ME 375: 0.375%). We assessed the larvicidal activity in the short term and after several days of exposure of pure isofuranodiene and its MEs against the filariasis vector Culex quinquefasciatus. The impact of ME-based larvicide at sublethal concentrations on adult emergence was evaluated. Finally, to shed light on potential ecotoxicology risks for nontarget invertebrates, MEs were tested on the aquatic microcrustacean Daphnia magna and on the earthworm Eisenia fetida. Pure isofuranodiene and S. olusatrum leaf essential oil, used as controls, showed their potential as mosquito larvicidal agents (LC50 of 29.2 and 18.6LL(-1), respectively). Isofuranodiene formulated in ME 750 was effective against C. quinquefasciatus larvae, leading to significant larval mortality over time and a marked decrease in adult emergence. Both isofuranodiene MEs showed little impact on the nontarget aquatic microcrustacean Daphnia magna (ME 750 and ME 375: mortality <19% after 48h of exposure at 32mL L-1 and 20mL L-1, respectively) as well as on earthworms (ME 750 and ME 375: no mortality and mortality <7% after 14days of exposure to 1000mgkg(-1), respectively), outlining their potential employ in vector control operations.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
40106 - Agronomy, plant breeding and plant protection; (Agricultural biotechnology to be 4.4)
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Pest Science
ISSN
1612-4758
e-ISSN
1612-4766
Volume of the periodical
92
Issue of the periodical within the volume
2
Country of publishing house
DE - GERMANY
Number of pages
13
Pages from-to
909-921
UT code for WoS article
000463146700045
EID of the result in the Scopus database
2-s2.0-85060602826