Phenolics of Aerial Parts of Gentiana lutea L. and Their Biological Activity

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027006%3A_____%2F21%3A10174307" target="_blank" >RIV/00027006:_____/21:10174307 - isvavai.cz</a>

Alternative codes found

RIV/61989592:15640/21:73610862

Result on the web

<a href="https://www.mdpi.com/2073-4395/11/7/1442/pdf" target="_blank" >https://www.mdpi.com/2073-4395/11/7/1442/pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/agronomy11071442" target="_blank" >10.3390/agronomy11071442</a>

Result language

angličtina

Original language name

Phenolics of Aerial Parts of Gentiana lutea L. and Their Biological Activity

Original language description

Gentiana lutea L. is a medicinal plant the roots of which are primarily used in treatments of various human digestive disorders, but also the production of alcoholic liquors. The roots (radix) of G. lutea are described in the European Pharmacopeia, but knowledge about the chemical composition and biological activities of its aerial parts is still limited. Thus, until today aerial parts of this species have not been used in medical treatments or consumed. Therefore, flowers, leaves, and stems extracts of G. lutea obtained by using four different extraction solvents (petrol ether, chloroform, ethanol, and water) were examined for their chemical composition and biological activities. High concentrations of salicylic acid, apigenin, and naringenin were recorded for ethanol stem extracts, while significant amounts of kaempferol were detected in leaves and flowers in chloroform and water extracts, respectively. The highest antioxidant potential was recorded for flower and stem petrol ether extracts with the lowest IC50 values, ranging from 94.46 +/- 9.45 to 105.38 +/- 10.54 mu g/mL. Ethanol extracts of flowers and stems showed moderate antioxidant activity (IC50 143.15 +/- 14.32 and 146.90 +/- 14.69 mu g/mL) as well as strong antimicrobial activity against Candida albicans (21.00 +/- 1.00 and 27.50 +/- 1.78 mm inhibition zones, respectively). In addition, ethanol extracts had higher antimycotic activity compared to naturally occurring phenolic compounds that are used as positive controls. Moreover, statistical analysis of the activities of plant extracts and single compounds showed that levels of chlorogenic and caffeic acids strongly correlate with the biological activities of the extracts, i.e., they are the main carriers of these biological activities. The presented results indicate the possible use of aerial parts of G. lutea as a natural preservative, as well as a antimicrobial agent, which significantly amplifies the benefits of this medicinal crop and greatly affects the sustainability of cultivated Gentiana plantation.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

40106 - Agronomy, plant breeding and plant protection; (Agricultural biotechnology to be 4.4)

Project

<a href="/en/project/EF16_019%2F0000827" target="_blank" >EF16_019/0000827: Plants as a tool for sustainable global development</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Agronomy-Basel

ISSN

2073-4395

e-ISSN

—

Volume of the periodical

11

Issue of the periodical within the volume

7

Country of publishing house

CH - SWITZERLAND

Number of pages

10

Pages from-to

1442

UT code for WoS article

000675927900001

EID of the result in the Scopus database

2-s2.0-85111401672