All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

EP05 Extraction of rosmarinic acid from Ocimum sanctum using Nades

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027006%3A_____%2F23%3A10176581" target="_blank" >RIV/00027006:_____/23:10176581 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    EP05 Extraction of rosmarinic acid from Ocimum sanctum using Nades

  • Original language description

    Rosmarinic acid (RA) and its derivatives exhibit biological actions against various diseases suchas cancer, diabetes, cardiovascular disease, neurodegenerative and inflammatory disorders. The most used conventional techniques for RA extraction from plants are Soxhlet extraction, maceration and new techniques have been introduced such as ultrasound-assisted extraction, microwave-assisted extraction, and supercritical fluid extraction using mainly organic solvents, e.g., ethanol, or acidified ethanol. Due to legislation restriction regarding ethanol, there is a demand for a solvent meeting the requirements (food industry). The solution could be Nades (Natural Deep Eutectic Solvents), which are very closed to the plants physiology. We studied mixtures of choline chloride:glucose, choline chloride:propane-1,2 diol and citric acid:glucose as examples of RA extraction using Nades. Dried, and ground basil leaves were mixed with the prepared Nades and extracted at laboratory temperature with constant stirring, then the mixture was analysed by HPLC. Extraction with citric acid:glucose mixtures is more selective and provides comparable or even higher yields of RA compared to methanol extraction.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

  • OECD FORD branch

    40106 - Agronomy, plant breeding and plant protection; (Agricultural biotechnology to be 4.4)

Result continuities

  • Project

    <a href="/en/project/QK1910103" target="_blank" >QK1910103: Czech Herbs for New Foods Promoting Population Health</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů