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DNA methylation pattern in human zygotes and developing embryos

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027014%3A_____%2F04%3A00010976" target="_blank" >RIV/00027014:_____/04:00010976 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    DNA methylation pattern in human zygotes and developing embryos

  • Original language description

    We have examined the pattern of DNA methylation in human embryos. In about half of the zygotes the paternal chromatin was less methylated than the maternal chromatin. In the other half, both pronuclei exhibited the same intensity of labeling. High levelsof labeling were observed for up to four cell stage, thereafter the decline of labeling was detected. Remethylation in some nuclei starts in late morulae. In the blastocyst, the inner cell mass showed a weaker intensity of labeling than the trophectoderm.

  • Czech name

    Úroveň methylace DNA v lidských zygotách a embryích

  • Czech description

    Distribuce mitochondrií v rekonstruovaných myších oocytech. Byla hodnocena distribuce mitochondrií v rekonstruovaných nezralých oocytech myši, kde značený karyoplast (GV) byl fúzován s neznačeným cytoplastem. Po fúzi došlo k rovnoměrnému rozptýlení mitochondrií v cytoplazmě. Rychlost distribuce je však závislá na stádiu buněčného cyklu.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA524%2F02%2F0032" target="_blank" >GA524/02/0032: Meiotic and mitotic division: role of the cytoplasm and the nucleus</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2004

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Reproduction

  • ISSN

    1470-1626

  • e-ISSN

  • Volume of the periodical

    128

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    6

  • Pages from-to

    703-708

  • UT code for WoS article

  • EID of the result in the Scopus database