DNA methylation pattern in human zygotes and developing embryos
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027014%3A_____%2F04%3A00010976" target="_blank" >RIV/00027014:_____/04:00010976 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
DNA methylation pattern in human zygotes and developing embryos
Original language description
We have examined the pattern of DNA methylation in human embryos. In about half of the zygotes the paternal chromatin was less methylated than the maternal chromatin. In the other half, both pronuclei exhibited the same intensity of labeling. High levelsof labeling were observed for up to four cell stage, thereafter the decline of labeling was detected. Remethylation in some nuclei starts in late morulae. In the blastocyst, the inner cell mass showed a weaker intensity of labeling than the trophectoderm.
Czech name
Úroveň methylace DNA v lidských zygotách a embryích
Czech description
Distribuce mitochondrií v rekonstruovaných myších oocytech. Byla hodnocena distribuce mitochondrií v rekonstruovaných nezralých oocytech myši, kde značený karyoplast (GV) byl fúzován s neznačeným cytoplastem. Po fúzi došlo k rovnoměrnému rozptýlení mitochondrií v cytoplazmě. Rychlost distribuce je však závislá na stádiu buněčného cyklu.
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA524%2F02%2F0032" target="_blank" >GA524/02/0032: Meiotic and mitotic division: role of the cytoplasm and the nucleus</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2004
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Reproduction
ISSN
1470-1626
e-ISSN
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Volume of the periodical
128
Issue of the periodical within the volume
4
Country of publishing house
GB - UNITED KINGDOM
Number of pages
6
Pages from-to
703-708
UT code for WoS article
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EID of the result in the Scopus database
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