Prebiotic effects of a novel combination of galactooligosaccharides and maltodextrins  

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027014%3A_____%2F15%3A%230002220" target="_blank" >RIV/00027014:_____/15:#0002220 - isvavai.cz</a>

Alternative codes found

RIV/60460709:41210/15:67887 RIV/00216208:11130/15:10316074 RIV/00064203:_____/15:10316074

Result on the web

<a href="http://www.vuzv.cz/sites/File/_privat/15067.pdf" target="_blank" >http://www.vuzv.cz/sites/File/_privat/15067.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1089/jmf.2013.0187" target="_blank" >10.1089/jmf.2013.0187</a>

Result language

angličtina

Original language name

Prebiotic effects of a novel combination of galactooligosaccharides and maltodextrins  

Original language description

Prebiotics are used for stimulating the growth of beneficial microorganisms in the gut. However, it is very difficult to find a suitable prebiotic mixture that exclusively supports the growth of beneficial microbes such as bifidobacteria and lactobacilli. We tested the effects of a prebiotic mixture in vitro by incubating it with fecal samples and in vivo by administration of the prebiotic supplement to healthy adult volunteers, followed by analysis of their fecal microbiota. The effect of the oligosaccharides on bacterial metabolism was studied by analyzing short-chain fatty acid (SCFA) production in vitro and the SCFA pattern for the stool samples of volunteers. In the in vitro test, a higher proportion of bifidobacteria (25.77%) was seen in the total bacterial population after cultivation on a prebiotic mixture than on the control medium (7.94%). The gram-negative anaerobe count significantly decreased from 8.70 to 6.40 log CFU/g (from 35.21% to 0.60%) and the Escherichia coli count decreased from 7.41 to 6.27 log CFU/g (from 1.78% to 0.44%). Administration of a prebiotic mixture in vivo (9 g of galactooligosaccharides [GOS] + 1 g of maltodextrins; daily for 5 days) significantly increased the fecal bifidobacterial count from 9.45 to 9.83 log CFU/g (from 40.80% to 53.85% of total bacteria) and reduced the E. coli count from 7.23 to 6.28 log CFU/g (from 55.35% to 45.06% of total bacteria). The mixture comprising GOS and maltodextrins thus exhibited bifidogenic properties, promoting the performance of bifidobacteria by boosting their growth and inhibiting the growth of undesirable bacteria.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EE - Microbiology, virology

OECD FORD branch

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Project

<a href="/en/project/QJ1210093" target="_blank" >QJ1210093: New methods for production, quality control and the effects of probiotic foods</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Medicinal Food 

ISSN

1096-620X

e-ISSN

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Volume of the periodical

18

Issue of the periodical within the volume

6

Country of publishing house

KR - KOREA, REPUBLIC OF

Number of pages

5

Pages from-to

685-689

UT code for WoS article

000360531500010

EID of the result in the Scopus database

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