Analysis of selection signatures in the beef cattle genome
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027014%3A_____%2F19%3AN0000269" target="_blank" >RIV/00027014:_____/19:N0000269 - isvavai.cz</a>
Alternative codes found
RIV/60460709:41210/19:80499
Result on the web
<a href="https://www.agriculturejournals.cz/publicFiles/226_2019-CJAS.pdf" target="_blank" >https://www.agriculturejournals.cz/publicFiles/226_2019-CJAS.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.17221/226/2019-CJAS" target="_blank" >10.17221/226/2019-CJAS</a>
Alternative languages
Result language
angličtina
Original language name
Analysis of selection signatures in the beef cattle genome
Original language description
This study aimed to evaluate the impact of selection on the genome structure of beef cattle through identification of selection signatures reflecting the breeding standard of each breed and to discover potential functional genetic variants to improve performance traits. Genotyping data of six beef breeds (Aberdeen Angus, Hereford, Limousin, Charolais, Piedmontese and Romagnola) were used to perform genome-wide scans for selection signatures. The approaches applied were based on an assumption that selection leads to linkage disequilibrium or to a decrease of genetic variability in genomic regions containing genotypes connected with favourable phenotypes. Thus, the selection signatures were analysed based on Wright’s FST index, distribution of runs of homozygosity segments in the beef genome and determination of linkage disequilibrium variability between breeds. The number and length of detected selection signals were different depending on the breeds and methodological approaches. As expected due to the breeding goals of analysed breeds, common signals were located on autosomes 2, 6, 7, 13 and 20 close to the genes associated with coat colour (KIT, KDR), muscle development (GDF9, GHRH, GHR), double muscling (MSTN), meat tenderness (CAST) and intramuscular fat content (SCD). But, across the genomes of analysed breeds, unique selection signals were found as well. The subsequent analysis of those single nucleotide polymorphism markers can be beneficial for the genetic progress of studied breeds in future.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
40203 - Husbandry
Result continuities
Project
<a href="/en/project/QK1910059" target="_blank" >QK1910059: Use of genomic information and optimization of beef cattle breeding programs</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Czech Journal of Animal Science
ISSN
1212-1819
e-ISSN
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Volume of the periodical
64
Issue of the periodical within the volume
12
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
13
Pages from-to
491-503
UT code for WoS article
000503837600003
EID of the result in the Scopus database
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