Scientific and technological approaches to improve SCNT efficiency in farm animals and pets

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027014%3A_____%2F21%3AN0000057" target="_blank" >RIV/00027014:_____/21:N0000057 - isvavai.cz</a>
Result on the web
<a href="http://bioscientifica.com" target="_blank" >http://bioscientifica.com</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1530/REP-20-0653" target="_blank" >10.1530/REP-20-0653</a>

Result language
angličtina
Original language name
Scientific and technological approaches to improve SCNT efficiency in farm animals and pets
Original language description
The birth of Dolly through somatic cell nuclear transfer (SCNT) was a major scientific breakthrough of the last century. Yet, while significant progress has been achieved across the technics required to reconstruct and in vitro culture nuclear transfer embryos, SCNT outcomes in terms of offspring production rates are still limited. Here, we provide a snapshot of the practical application of SCNT in farm animals and pets. Moreover, we suggest a path to improve SCNT through alternative strategies inspired by the physiological reprogramming in male and female gametes in preparation for the totipotency required after fertilization.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10604 - Reproductive biology (medical aspects to be 3)

Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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