Sperm chromatin integrity in young men with no experiences of infertility and men from idiopathic infertility couples

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F09%3A%230000506" target="_blank" >RIV/00027162:_____/09:#0000506 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Sperm chromatin integrity in young men with no experiences of infertility and men from idiopathic infertility couples

Original language description

Damage to the genetic component of sperm seems to play the main role in the majority of cases where current approaches fail to reveal the specific cause of male infertility. In the present study, we compared semen quality in men assigned to two defined groups: men from couples with unexplained infertility - idiopathic infertility (A) and young men with no experiences of infertility (B). All samples were examined by standard ejaculate analysis and Sperm chromatin Structure Assay (SCSA). Sperm chromatin damage was significantly higher in men from group A in comparison with men from group B. Similar results were obtained by comparison of men from group A (all men were normozoospermic) and normozoospermic men from groups B. According to these results, we can suppose that chromatin disorders may be the causal factor of subfertility or infertility in some of these men. SCSA is a method which facilitates the identification of infertile men who otherwise show normal semen variables.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

<a href="/en/project/1QS500390506" target="_blank" >1QS500390506: Impact of environmental and genetic factors on men fertility</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Andrologia

ISSN

0303-4569

e-ISSN

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Volume of the periodical

41

Issue of the periodical within the volume

3

Country of publishing house

US - UNITED STATES

Number of pages

10

Pages from-to

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UT code for WoS article

000265480700002

EID of the result in the Scopus database

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