Investigation of Chromosome Aneuploidies in Early Porcine Embryos Using Comparative Genomic Hybridization

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F09%3A%230000564" target="_blank" >RIV/00027162:_____/09:#0000564 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Investigation of Chromosome Aneuploidies in Early Porcine Embryos Using Comparative Genomic Hybridization
Original language description
The objectives of this study were established to investigate the whole chromosome set of in vivo obtained early pig embryos, applying methods of whole genome amplification and comparative genomic hybridization (CGH). 11 (14.3%) of the 77 pig embryos examined, were observed to be aneuploid. We found chromosome errors comprising loss/gain of one or few chromosomes (10.4%) but also extensive chromosome imbalances (3.9%). Chromosomes 8, 11, 12, 13, 17, and X were most frequently involved in aneuploidies, when compared to chromosomes 2, 9, and 18, which were rarely involved in chromosome errors.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Project
<a href="/en/project/QH81068" target="_blank" >QH81068: The study on causes of early embryo mortality by comparative genome hybridization</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2009
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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