Male obesity and age in relationship to semen parameters and sperm chromatin integrity

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F11%3A%230000738" target="_blank" >RIV/00027162:_____/11:#0000738 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Male obesity and age in relationship to semen parameters and sperm chromatin integrity
Original language description
Obesity can adversely affect human health. While obesity can disturb the hormonal profile of the female organism and is associated with fertility loss, little is known about the effect of male obesity. Semen samples of 153 donors were selected from couples attending an infertility clinic, who had tried for 12 months or more to achieve pregnancy without success. Age and body mass index (BMI) of the men was recorded. Semen samples were assessed for volume, sperm concentration, motility and morphology. Sperm chromatin integrity was measured by sperm chromatin structure assay. Quality of sperm chromatin condensation was assessed by toluidine blue, aniline blue and chromomycin A3 staining. We can conclude that the impact of elevated BMI on the parameters investigated was not proven. On the other hand, ejaculate quality appeared to be affected by ageing. The impact was reflected by chromatin integrity, which is a factor that can substantially affect fertility in men, rather than by basic spe
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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