Host response in rabbits to infection with Pasteurella multocida serogroup F strains originating from fowl cholera

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F11%3A%230000745" target="_blank" >RIV/00027162:_____/11:#0000745 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Host response in rabbits to infection with Pasteurella multocida serogroup F strains originating from fowl cholera

Original language description

The ability of two avian P. multocida serogroup F strains to induce disease in rabbits was investigated. Two groups of 18 Pasteurella-free rabbits each were intranasally challenged with strains isolated from chickens and turkeys respectively. Half of theanimals in each challenge group were immunosuppressed using dexamethasone. All the challenged rabbits exhibited clinical signs of peracute septicaemic disease, ending with shock, and died or were euthanased in the terminal stages of the disease 1-2 dayspost-infection. Gross pathological changes included systemic vascular collapse and vascular leak syndrome. Hyperaemia, haemorrhage, oedema, inflammatory cell infiltrates, focal necrosis and degenerative changes were observed histologically in parenchymatous organs. This is the first study directly demonstrating that avian P. multocida serogroup F strains are highly virulent in rabbits and that avian hosts cannot be excluded as a possible source of rabbit infection with serogroup F.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FN - Epidemiology, infection diseases and clinical immunology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Canadian Journal of Veterinary Research-REVUE CANADIENNE DE RECHERCHE VETERINAIRE

ISSN

0830-9000

e-ISSN

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Volume of the periodical

75

Issue of the periodical within the volume

3

Country of publishing house

CA - CANADA

Number of pages

9

Pages from-to

200-208

UT code for WoS article

000299528000006

EID of the result in the Scopus database

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