Gene expression in the chicken caecum in response to infections with non-typhoid Salmonella

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F14%3A%230001158" target="_blank" >RIV/00027162:_____/14:#0001158 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1186/s13567-014-0119-2" target="_blank" >http://dx.doi.org/10.1186/s13567-014-0119-2</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/s13567-014-0119-2" target="_blank" >10.1186/s13567-014-0119-2</a>

Result language

angličtina

Original language name

Gene expression in the chicken caecum in response to infections with non-typhoid Salmonella

Original language description

Chickens can be infected with Salmonella enterica at any time during their life. However, infections within the first hours and days of their life are epidemiologically the most important, as newly hatched chickens are highly sensitive to Salmonella infection. Salmonella is initially recognized in the chicken caecum by TLR receptors and this recognition is followed by induction of chemokines, cytokines and many effector genes. This results in infiltration of heterophils, macrophages, B-and T-lymphocytesand changes in total gene expression in the caecal lamina propria. The highest induction in expression is observed for matrix metalloproteinase 7 (MMP7). Expression of this gene is increased in the chicken caecum over 4000 fold during the first 10 daysafter the infection of newly hatched chickens. Additional highly inducible genes in the caecum following S. Enteritidis infection include immune responsive gene 1 (IRG1), serum amyloid A (SAA), extracellular fatty acid binding protein (Ex

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

GJ - Diseases and animal vermin, veterinary medicine

OECD FORD branch

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Project

<a href="/en/project/ED0006%2F01%2F01" target="_blank" >ED0006/01/01: Center for Advanced Microbiology & Immunology Research in Veterinary Medicine</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Veterinary Research

ISSN

0928-4249

e-ISSN

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Volume of the periodical

45

Issue of the periodical within the volume

dec

Country of publishing house

GB - UNITED KINGDOM

Number of pages

7

Pages from-to

119-126

UT code for WoS article

000345961100001

EID of the result in the Scopus database

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