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Changes in lymphocyte function and subset counts in cats with spontaneous chronic kidney disease

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F16%3AN0000092" target="_blank" >RIV/00027162:_____/16:N0000092 - isvavai.cz</a>

  • Alternative codes found

    RIV/62157124:16170/16:43874269 RIV/62157124:16270/16:43874269

  • Result on the web

    <a href="http://www.agriculturejournals.cz/publicFiles/197676.pdf" target="_blank" >http://www.agriculturejournals.cz/publicFiles/197676.pdf</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.17221/282/2015-VETMED" target="_blank" >10.17221/282/2015-VETMED</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Changes in lymphocyte function and subset counts in cats with spontaneous chronic kidney disease

  • Original language description

    Chronic kidney disease alters the immune response in humans and dogs and it is thought to be one of the causes of immunosuppression in cats. Haematological, biochemical, and immunological examinations were performed on blood samples obtained from 20 cats with chronic kidney disease, and were compared with the results of 18 healthy cats. In cats with chronic kidney disease, statistically significantly lower numbers of total lymphocytes (P < 0.01), especially T lymphocytes (P < 0.001), were observed. When the results were compared with the lymphocyte transformation test in healthy cats, decreased responses to phytohaemaglutinin, concanavalin A, and pokeweed mitogen were found in cats with chronic kidney disease. Our results document an alteration of counts and activity of lymphocytes in cats with chronic kidney disease. Thus, higher usceptibility to infection may be expected in these patients.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    GJ - Diseases and animal vermin, veterinary medicine

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/LO1218" target="_blank" >LO1218: Healthy animal as a source of wholesome food</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Veterinární medicína

  • ISSN

    0375-8427

  • e-ISSN

  • Volume of the periodical

    61

  • Issue of the periodical within the volume

    10

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    7

  • Pages from-to

    553-559

  • UT code for WoS article

    000386020600003

  • EID of the result in the Scopus database