Changes in lymphocyte function and subset counts in cats with spontaneous chronic kidney disease
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F16%3AN0000092" target="_blank" >RIV/00027162:_____/16:N0000092 - isvavai.cz</a>
Alternative codes found
RIV/62157124:16170/16:43874269 RIV/62157124:16270/16:43874269
Result on the web
<a href="http://www.agriculturejournals.cz/publicFiles/197676.pdf" target="_blank" >http://www.agriculturejournals.cz/publicFiles/197676.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.17221/282/2015-VETMED" target="_blank" >10.17221/282/2015-VETMED</a>
Alternative languages
Result language
angličtina
Original language name
Changes in lymphocyte function and subset counts in cats with spontaneous chronic kidney disease
Original language description
Chronic kidney disease alters the immune response in humans and dogs and it is thought to be one of the causes of immunosuppression in cats. Haematological, biochemical, and immunological examinations were performed on blood samples obtained from 20 cats with chronic kidney disease, and were compared with the results of 18 healthy cats. In cats with chronic kidney disease, statistically significantly lower numbers of total lymphocytes (P < 0.01), especially T lymphocytes (P < 0.001), were observed. When the results were compared with the lymphocyte transformation test in healthy cats, decreased responses to phytohaemaglutinin, concanavalin A, and pokeweed mitogen were found in cats with chronic kidney disease. Our results document an alteration of counts and activity of lymphocytes in cats with chronic kidney disease. Thus, higher usceptibility to infection may be expected in these patients.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
GJ - Diseases and animal vermin, veterinary medicine
OECD FORD branch
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Result continuities
Project
<a href="/en/project/LO1218" target="_blank" >LO1218: Healthy animal as a source of wholesome food</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Veterinární medicína
ISSN
0375-8427
e-ISSN
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Volume of the periodical
61
Issue of the periodical within the volume
10
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
7
Pages from-to
553-559
UT code for WoS article
000386020600003
EID of the result in the Scopus database
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