All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

The effect of foodborne sertraline on rainbow trout (Oncorhynchus mykiss)

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F20%3AN0000017" target="_blank" >RIV/00027162:_____/20:N0000017 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14160/20:00117998 RIV/62156489:43210/20:43917137 RIV/62157124:16170/20:43878781 RIV/62157124:16270/20:43878781 RIV/62157124:16370/20:43878781

  • Result on the web

    <a href="https://www.sciencedirect.com/science/article/pii/S0048969719350740?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0048969719350740?via%3Dihub</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.scitotenv.2019.135082" target="_blank" >10.1016/j.scitotenv.2019.135082</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    The effect of foodborne sertraline on rainbow trout (Oncorhynchus mykiss)

  • Original language description

    The worldwide consumption of antidepressants is raising as well as their concentrations in the aquatic environment. This increases the risk of food chain contamination and bioaccumulation in aquatic biota. The aim of this study was to describe a potential risk of sertraline as a pollutant from water environment, wherein rainbow trout (Oncorhynchus mykiss) has been chosen as the test organism, because predatory fish are on the top of the food chain in the aquatic environment. The effects of foodborne sertraline were tested on rainbow trout during a 28-day toxicity test according to OECD 215 method. Sertraline was incorporated in commercial feed at a dose of 4.4 µg/kg (environmental concentration), 42 µg/kg and 400 µg/kg. The results confirmed that sertraline has a significant effect on fish behaviour, resulting in suppression of the escape reflex and increased resistance to stress. Moreover, increased Fultońs condition factor was found in fish fed with the highest concentration of sertraline. Haematological analysis revealed a statistically significant increase in the number of neutrophilic bands and neutrophil/lymphocyte ratio, and decreased number of lymphocytes. The results of biochemical examination showed a statistically significant decrease in ammonia and lactate concentrations and histological examination revealed changes in gills and caudal kidney. Although sertraline reduces stress in fish, the decline in nonspecific immunity is a risk to fish population stability.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    40401 - Agricultural biotechnology and food biotechnology

Result continuities

  • Project

    <a href="/en/project/EF16_019%2F0000869" target="_blank" >EF16_019/0000869: Sustainable production of healthy fish in various aquaculture systems - PROFISH</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2020

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Science of the Total Environment

  • ISSN

    0048-9697

  • e-ISSN

    1879-1026

  • Volume of the periodical

    708

  • Issue of the periodical within the volume

    MAR 15 2020

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    7

  • Pages from-to

    135082

  • UT code for WoS article

    000506214900154

  • EID of the result in the Scopus database

    2-s2.0-85076611570