The distribution of antibiotic resistance genes in chicken gut microbiota commensals
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F21%3AN0000028" target="_blank" >RIV/00027162:_____/21:N0000028 - isvavai.cz</a>
Alternative codes found
RIV/00216305:26220/21:PU141272
Result on the web
<a href="https://www.nature.com/articles/s41598-021-82640-3" target="_blank" >https://www.nature.com/articles/s41598-021-82640-3</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/s41598-021-82640-3" target="_blank" >10.1038/s41598-021-82640-3</a>
Alternative languages
Result language
angličtina
Original language name
The distribution of antibiotic resistance genes in chicken gut microbiota commensals
Original language description
Antibiotic resistance in bacterial pathogens or several indicator bacteria is commonly studied but the extent of antibiotic resistance in bacterial commensals colonising the intestinal tract is essentially unknown. In this study, we aimed to investigate the presence of horizontally acquired antibiotic resistance genes among chicken gut microbiota members in 259 isolates with known whole genomic sequences. Altogether 124 isolates contained at least one gene coding for antibiotic resistance. Genes coding for the resistance to tetracyclines (detected in 101 isolates), macrolide-lincosamide-streptogramin B antibiotics (28 isolates) and aminoglycosides (25 isolates) were the most common. The most frequent tetracycline resistance genes were tet(W), tet(32), tet(O) and tet(Q). Lachnospiraceae and Ruminococcaceae frequently encoded tet(W). Lachnospiraceae commonly coded also for tet(32) and tet(O). The tet(44) gene was associated with Erysipelotrichaceae and tet(Q) was detected in the genomes of Bacteroidaceae and Porphyromonadaceae. Without any bias we have shown that antibiotic resistance is quite common in gut commensals. However, a comparison of codon usage showed that the above-mentioned families represent the most common current reservoirs but probably not the original host of the detected resistances.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
40301 - Veterinary science
Result continuities
Project
<a href="/en/project/GJ18-15238Y" target="_blank" >GJ18-15238Y: Chicken gut resistome - the incidence and dissemination of antibiotic resistance genes in chicken gut microbiota</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Scientific Reports
ISSN
2045-2322
e-ISSN
2045-2322
Volume of the periodical
11
Issue of the periodical within the volume
1
Country of publishing house
GB - UNITED KINGDOM
Number of pages
10
Pages from-to
"3290"
UT code for WoS article
000617644900003
EID of the result in the Scopus database
2-s2.0-85100753935